4.8 Article

Postoperative circulating tumor DNA could guide CRC adjuvant treatment

Journal

NATURE MEDICINE
Volume 29, Issue 1, Pages 39-40

Publisher

NATURE PORTFOLIO
DOI: 10.1038/s41591-022-02119-0

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The ongoing CIRCULATE-Japan trial is investigating the role of ctDNA-based molecular residual disease testing in patients with resectable colorectal cancer after surgery. An interim analysis of GALAXY, a prospective observational arm, confirms ctDNA as a prognostic and predictive biomarker.
The large, ongoing CIRCULATE-Japan trial is investigating the role of circulating tumor DNA (ctDNA)-based molecular residual disease testing in patients with resectable colorectal cancer after radical surgery. An interim analysis of GALAXY, a prospective, observational arm of CIRCULATE-Japan, establishes ctDNA as a prognostic and predictive biomarker.

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