4.1 Article

Hemophagocytic Lymphohistiocytosis Following COVID-19 Infection

Journal

CUREUS JOURNAL OF MEDICAL SCIENCE
Volume 15, Issue 1, Pages -

Publisher

SPRINGERNATURE
DOI: 10.7759/cureus.34307

Keywords

disseminated intravascular coagulation (dic); soluble interleukin receptors; inflammatory mediators; pancytopenia; hemophagocytic lymphohistiocytosis (hlh); covid 19

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A case of HLH secondary to dysregulated inflammatory response following COVID-19 is presented, highlighting the challenges in diagnosis and management.
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been associated with multiple inflammatory symptoms involving several organ systems, including hematologic manifestations. Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening syndrome caused by excessive inflammation in the absence of immune regulation. We present the case of a patient with HLH secondary to dysregulated inflammatory response following COVID-19; we also describe the diagnostic and management challenges associated with the condition.

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