Hands-on seminar for image-guided adaptive brachytherapy and intracavitary/interstitial brachytherapy for uterine cervical cancer

Editorial Material Oncology

Increasing global access to brachytherapy: The ABS 300 in 10 initiative and ongoing international efforts

Daniel G. Petereit

Summary: This article introduces the GEC-ESTRO/EMBRACE initiative, which is an educational platform for promoting image-guided adaptive brachytherapy worldwide. By developing CT and MRI compatible applicators, it has improved the treatment outcomes.

BRACHYTHERAPY (2022)

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Article Oncology

Better late than never: Brachytherapy is more important than timing in treatment of locally advanced cervical cancer

Travis-Riley K. Korenaga et al.

Summary: This study evaluated the impact of brachytherapy utilization and treatment duration on overall survival for cervical cancer patients. The results showed that completing standard of care treatment with concurrent chemoradiation therapy and brachytherapy within 8 weeks was associated with superior overall survival. Patients who received brachytherapy had better survival outcomes compared to those who only received external beam radiation therapy, regardless of treatment duration. Disparities in care for vulnerable populations were highlighted, emphasizing the importance of care coordination.

GYNECOLOGIC ONCOLOGY (2022)

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Article Biology

An Asian multi-national multi-institutional retrospective study comparing intracavitary versus the hybrid of intracavitary and interstitial brachytherapy for locally advanced uterine cervical carcinoma

Naoya Murakami et al.

Summary: This study compared the clinical outcomes between intracavitary brachytherapy (ICBT) and the hybrid of intracavitary and interstitial brachytherapy (HBT) for locally advanced cervical cancer patients. The results showed that, despite having more advanced disease, patients in the HBT group did not demonstrate superior outcomes in terms of local control, progression-free survival, or overall survival.

JOURNAL OF RADIATION RESEARCH (2022)

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Article Biology

Japanese Society for Radiation Oncology Consensus Guidelines of combined intracavitary and interstitial brachytherapy for gynecological cancers

Naoya Murakami et al.

Summary: This article discusses the effectiveness and safety of intracavitary and interstitial brachytherapy (IC/IS) in treating large and irregularly shaped uterine cervical cancer patients. Compared to conventional intracavitary brachytherapy (ICBT), IC/IS is more invasive and thus has a slower implementation speed. The article aims to provide practical and comprehensive guidance for radiation oncologists and medical physicists who wish to start IC/IS, and to accelerate the nationwide utilization of IC/IS by sharing the Japanese approach to managing locally advanced uterine cervical cancer.

JOURNAL OF RADIATION RESEARCH (2022)

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Article Oncology

Brachytherapy training survey among radiation oncology residents in Europe

Alina Emiliana Sturdza et al.

Summary: This study investigated the current state of brachytherapy (BT) training among radiation oncology trainees in Europe. The results showed that although the trainees considered independent BT practice to be important, they lacked confidence in achieving this goal. Efforts are needed to develop and implement a formal and comprehensive BT curriculum to address this gap.

RADIOTHERAPY AND ONCOLOGY (2022)

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Article Oncology

Large volume was associated with increased risk of acute non-hematologic adverse events in the hybrid of intracavitary and interstitial brachytherapy for locally advanced uterine cervical cancer: preliminary results of prospective phase I/II clinical trial

Naoya Murakami et al.

Summary: The feasibility and reproducibility of the hybrid of intracavitary and interstitial brachytherapy were demonstrated in a multi-center prospective clinical trial. High-risk clinical target volume >= 35 ml was associated with an increased risk of any grade of acute non-hematologic adverse events related to the hybrid of intracavitary and interstitial brachytherapy.

JAPANESE JOURNAL OF CLINICAL ONCOLOGY (2022)

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Article Oncology