The use of sealing hemostat patch (HEMOPATCH®) in laparotomic myomectomy: a prospective case-control study

Purpose Uterine myomas are the most common gynecological disease. In these cases, a myomectomy is performed traditionally laparotomically. However, alternatives have been widely used, including laparoscopic, endoscopic, and robotic surgery. During these techniques, diffuse parenchymatous bleeding remains one of the main intraoperative and postoperative complications and sometimes requires unplanned hysterectomies. Recently, hemostatic agents and sealants have been used to prevent excessive blood loss during surgical repair. Methods We propose a prospective case-control study on the use of a sealing hemostat patch (HEMOPATCH((R))) on uterine sutures in laparotomic myomectomy. In the period between July 2016 and April 2017, 46 patients with symptomatic uterine fibromatosis underwent surgery. They were divided into two groups of 23 patients, with different treatments in the hemostatic phase of oozing bleeding. HEMOPATCH((R)) is applied in group A, and spray electrocoagulation is applied in group B. Results In group A, we achieve faster hemostasis (p < 0.05), than in group B. We report a significantly lower C-reactive protein value on the second and third days after surgery for group A compared to group B. Conclusions HEMOPATCH((R)), during laparotomic myomectomy, is a valid alternative solution for obtaining rapid hemostasis and consequently intraoperative and postoperative bleeding. Furthermore, we suggest that a lower inflammatory peritoneal state is probably correlated with the barrier effect of the patch on the suture.

Automated summary

We conducted a prospective case-control study on the use of a sealing hemostat patch (HEMOPATCH(R)) in laparoscopic myomectomy. The results showed that patients in group A achieved faster hemostasis and had lower inflammatory response after surgery compared to group B.