Research and Application of N-Ts Cyanamides in Organic Synthesis

N-Ts cyanamide, which has been widely used in the construction of nitrogen-containing framework, is one of the efficient and practical multifunctional synthetic precursors in organic synthesis. The progress in application of N-Ts cyanamide according to the reaction types is summarized, including the application in cyanation, cyclization reaction via cyanamide anion, cyanamidation, sulfonylation and cyclization reaction via cyano-group. The future development direction of this field is also prospected.

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This article summarizes the progress in the application of N-Ts cyanamide in organic synthesis, including cyanation, cyclization reaction via cyanamide anion, cyanamidation, sulfonylation, and cyclization reaction via cyano-group. The future development direction in this field is also prospected.