☆ 4.7 Article

Sciadonic acid attenuates high-fat diet-induced obesity in mice with alterations in the gut microbiota

FOOD & FUNCTION (2023)

Related references

Note: Only part of the references are listed.

Article Chemistry, Applied

Identification of key genes and enzymes contributing to nutrition conversion of Torreya grandis nuts during post-ripening process

Lili Song et al.

Summary: This study uncovers the molecular basis of nutrition conversion in Torreya grandis seeds and suggests that sucrose phosphate synthase, dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, glycerol-3-phosphate acyltransferase, and pyruvate kinase may play key roles in nutrition conversion.

FOOD CHEMISTRY (2022)

Add to Collection

Article Biochemistry & Molecular Biology

Copper (Cu) induced changes of lipid metabolism through oxidative stress-me diated autophagy and Nrf2/PPARγ pathways

Chong-Chao Zhong et al.

Summary: Oxidative stress and autophagy are involved in copper-induced lipid deposition, and Nrf2 plays a crucial role in this process, regulating lipid metabolism and lipogenesis. Additionally, oxidative stress promotes Nrf2 recruitment to the PPAR gamma promoter, leading to target gene transcription and subsequent lipogenesis.

JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2022)

Add to Collection

Article Agriculture, Multidisciplinary

Different typical dietary lipid consumption affects the bile acid metabolism and the gut microbiota structure: an animal trial using Sprague-Dawley rats

Zhan Ye et al.

Summary: This study demonstrated that different dietary lipids have varying effects on bile acid metabolism, which may be related to their modulation of gut microbiota structure. Dietary lipids rich in saturated fatty acids and monounsaturated fatty acids are more likely to decrease the re-absorption of bile acid in the colon, while dietary lipids rich in polyunsaturated fatty acids may help maintain bile acid metabolic balance by regulating gut microbiota abundance.

JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2022)

Add to Collection

Article Food Science & Technology

Anti-diabetic effect of aloin via JNK-IRS1/PI3K pathways and regulation of gut microbiota

Ruting Zhong et al.

Summary: The research indicates that aloin can improve insulin resistance by activating the IRS1/PI3K/Akt signaling pathway and regulating gut microbiota, suggesting its potential as a candidate for diabetic therapy.

FOOD SCIENCE AND HUMAN WELLNESS (2022)

Add to Collection

Article Food Science & Technology

Chinese Torreya grandis cv. Merrillii seed oil affects obesity through accumulation of sciadonic acid and altering the composition of gut microbiota

Huan Wang et al.

Summary: This study found that Torreya grandis seed oil can improve lipid metabolism and achieve it through changes in gut microbiota composition and functionality. The oil significantly reduced the rate of body mass gain and liver fat index, and decreased the levels of total cholesterol, triglycerides, and low-density lipoprotein cholesterol. Additionally, it altered the fatty acid composition and alleviated pathological damage to the liver caused by a high-fat diet.

FOOD SCIENCE AND HUMAN WELLNESS (2022)

Add to Collection

Article Food Science & Technology

Dose-dependent effects of apple pectin on alleviating high fat-induced obesity modulated by gut microbiota and SCFAs

Yuanyuan Zhao et al.

Summary: This study found a dose-dependent relationship between pectin intake and changes in body weight, fat accumulation, serum triglyceride levels, and acetate and propionate concentrations. Additionally, pectin was found to modulate the gut microbiota and enhance short-chain fatty acid production, leading to attenuations in colonic injury and liver steatosis.

FOOD SCIENCE AND HUMAN WELLNESS (2022)

Add to Collection

Article Pharmacology & Pharmacy

PPARα regulates the expression of human arylacetamide deacetylase involved in drug hydrolysis and lipid metabolism

Tomomi Morikawa et al.

Summary: This study demonstrated the regulation of human AADAC by PPAR alpha through binding to DR1, and the significance of AADAC in lipid accumulation.

BIOCHEMICAL PHARMACOLOGY (2022)

Add to Collection

Review Medicine, Research & Experimental

The links between gut microbiota and obesity and obesity related diseases

Jiafeng Geng et al.

Summary: The obesity epidemic has become a global public health crisis, with the pathophysiological mechanisms still being unraveled. Gut microbiota plays a crucial role in obesity and related diseases, influencing obesity progression through changes in composition and metabolites, with potential therapeutic implications in targeting relevant metabolic pathways.

BIOMEDICINE & PHARMACOTHERAPY (2022)

Add to Collection

Article Food Science & Technology

Licorice extract ameliorates hyperglycemia through reshaping gut microbiota structure and inhibiting TLR4/NF-κB signaling pathway in type 2 diabetic mice

Yongli Zhang et al.

Summary: Licorice extract improves blood glucose levels and metabolic functions in type 2 diabetic mice by regulating the gut microbiota and colon signaling pathway.

FOOD RESEARCH INTERNATIONAL (2022)

Add to Collection

Article Food Science & Technology

Probiotic-fermented rice buckwheat alleviates high-fat diet-induced hyperlipidemia in mice by suppressing lipid accumulation and modulating gut microbiota

Jing Yan et al.

Summary: The probiotics-fermented rice buckwheat (FRB) significantly reduced weight gain and visceral obesity, improved dyslipidemia, alleviated oxidative stress and chronic inflammation in high-fat diet-induced mice. Furthermore, FRB intervention inhibited hepatic cholesterol synthesis, promoted lipolysis, and reversed gut dysbiosis induced by high-fat diet, demonstrating its beneficial effects on hyperlipidemia.

FOOD RESEARCH INTERNATIONAL (2022)

Add to Collection

Article Biochemistry & Molecular Biology

Angelica sinensis polysaccharide improves rheumatoid arthritis by modifying the expression of intestinal Cldn5, Slit3 and Rgs18 through gut microbiota

Qing Hu et al.

Summary: This study found that Angelica sinensis polysaccharide (ASP) could improve rheumatoid arthritis (RA) by regulating gut microbiota and gene expression, revealing a positive relationship between dietary patterns and RA.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022)

Add to Collection

Article Food Science & Technology

Ganoderma lucidum protease hydrolyzate on lipid metabolism and gut microbiota in high-fat diet fed rats

Yu Xiong et al.

Summary: The study evaluates the effects of Ganoderma lucidum protease hydrolysate (GLPH) on lipid metabolism and intestinal flora in rats fed a high-fat diet. The results show that GLPH reduces triglycerides, total cholesterol, low-density lipoprotein cholesterol, alanine aminotransferase, and aspartate aminotransferase levels, while increasing high-density lipoprotein cholesterol. GLPH also alters the composition of intestinal flora and reduces the abundance of potentially harmful bacteria.

FOOD BIOSCIENCE (2022)

Add to Collection

Article Nutrition & Dietetics

Antidiabetic effect of sciadonic acid on type 2 diabetic mice through activating the PI3K-AKT signaling pathway and altering intestinal flora

Lin Chen et al.

Summary: The study found that sciadonic acid (SA) could improve metabolic disorders and intestinal flora imbalance in patients with type 2 diabetes mellitus (T2DM), potentially by activating the PI3K/AKT/GLUT2 pathway, promoting glucose metabolism gene expression, and maintaining the stability of the intestinal flora.

FRONTIERS IN NUTRITION (2022)

Add to Collection

Article Biochemistry & Molecular Biology

Characterization of long-chain fatty acid-linked bile acids: a major conjugation form of 3β-hydroxy bile acids in feces

Hajime Takei et al.

Summary: This study compares the bile acid profiles in healthy stools obtained with and without alkaline hydrolysis, showing the presence of saponifiable bile acids and the esterification of certain acids. Further analysis reveals the constant presence of fatty acid-conjugated isobile acids (FA-isoBAs) in fecal samples, suggesting a potential role in gut physiology and pathophysiological conditions. The study provides insight into the establishment of gut microbiota and the development of esterified bile acids.

JOURNAL OF LIPID RESEARCH (2022)

Add to Collection

Article Biochemistry & Molecular Biology

The probiotic effects of AB23A on high-fat-diet-induced non-alcoholic fatty liver disease in mice may be associated with suppressing the serum levels of lipopolysaccharides and branched-chain amino acids

Fan Xia et al.

Summary: This study demonstrated that AB23A significantly improved the metabolic phenotype in HFD-fed mice by altering gut microbiota composition, reducing serum levels of lipopolysaccharide and branched chain amino acids, and modulating the expression of key proteins related to gut barrier function.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2021)

Add to Collection

Article Food Science & Technology

Effects of dibutyl phthalate on lipid metabolism in liver and hepatocytes based on PPARα/SREBP-1c/FAS/GPAT/AMPK signal pathway

Wang Zhang et al.

Summary: The study revealed that DBP can induce fatty liver disease by activating the PPAR alpha signaling pathway and inhibiting AMPK phosphorylation. The results indicated that DBP affects protein expression, leading to hyperlipidemia and abnormal liver function, which can be alleviated through the PPAR alpha/SREBP-1c/FAS/GPAT/AMPK signaling pathway.

FOOD AND CHEMICAL TOXICOLOGY (2021)

Add to Collection

Article Medicine, Research & Experimental

Dimethyl fumarate reduces oxidative stress, inflammation and fat deposition by modulation of Nrf2, SREBP-1c and NF-κB signaling in HFD fed mice

Atefeh Raesi Vanani et al.

Summary: The study found that DMF supplementation can reduce the development of NAFLD induced by HFD in mice by modulating transcription factors such as Nrf2, SREBP-1c, and NF-kappa B.

LIFE SCIENCES (2021)

Add to Collection

Article Nutrition & Dietetics

Protective Effects of Shrimp Peptide on Dextran Sulfate Sodium-Induced Colitis in Mice

Xingwei Xiang et al.

Summary: The study demonstrated the anti-inflammatory effects of shrimp peptide on a DSS-induced mouse model of UC, showing improvements in colitis severity, intestinal barrier integrity, inflammatory cytokines, antioxidant indices, and intestinal flora balance. These findings suggest that shrimp peptide has prophylactic and therapeutic effects on UC, indicating its broad medicinal applications.

FRONTIERS IN NUTRITION (2021)

Add to Collection

Article Nutrition & Dietetics

Whole Grain Qingke Attenuates High-Fat Diet-Induced Obesity in Mice With Alterations in Gut Microbiota and Metabolite Profile

Xipu Li et al.

Summary: Our study revealed that WGQK intervention in mice led to reduced body weight gain, improved glucose tolerance and lipid levels, alleviated liver function damage induced by HFD, and altered gut microbiota composition. WGQK also increased the abundance of tryptophan and histidine metabolism-related metabolites, as well as some unsaturated fatty acids.

FRONTIERS IN NUTRITION (2021)

Add to Collection

Article Food Science & Technology

Protective effects of Antarctic krill oil in dextran sulfate sodium-induced ulcerative colitis mice

Xiaoling Zhou et al.

Summary: Antarctic krill oil (KO) shows protective effects in mice with ulcerative colitis, reducing inflammatory cytokines production, improving intestinal health, regulating gut microbiota, and increasing short-chain fatty acids content.

JOURNAL OF FUNCTIONAL FOODS (2021)

Add to Collection

Review Medicine, Research & Experimental

Diets and drugs for weight loss and health in obesity-An update

Jan Aaseth et al.

Summary: Various diets and pharmaceutical aids have been developed to treat obesity, including low-fat, low-carbohydrate, Mediterranean diets, as well as GLP-1 agonists and other drugs. Successful weight loss seems to improve almost all biomarkers of obesity comorbidities.

BIOMEDICINE & PHARMACOTHERAPY (2021)

Add to Collection

Article Endocrinology & Metabolism

Clinical management and treatment of obesity in China

Qiang Zeng et al.

Lancet Diabetes & Endocrinology (2021)

Add to Collection

Review Nutrition & Dietetics

The Firmicutes/Bacteroidetes Ratio: A Relevant Marker of Gut Dysbiosis in Obese Patients?

Fabien Magne et al.

NUTRIENTS (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Short Administration of Combined Prebiotics Improved Microbial Colonization, Gut Barrier, and Growth Performance of Neonatal Piglets

Yujun Wu et al.

ACS OMEGA (2020)

Add to Collection

Article Allergy

Regulating metabolic inflammation by nutritional modulation

Hugo Charles-Messance et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2020)

Add to Collection

Article Endocrinology & Metabolism

Elevated levels of circulating short-chain fatty acids and bile acids in type 2 diabetes are linked to gut barrier disruption and disordered gut microbiota

Lijuan Zhao et al.

DIABETES RESEARCH AND CLINICAL PRACTICE (2020)

Add to Collection

Article Microbiology

Naringin Attenuates High Fat Diet Induced Non-alcoholic Fatty Liver Disease and Gut Bacterial Dysbiosis in Mice

Hongna Mu et al.

FRONTIERS IN MICROBIOLOGY (2020)

Add to Collection

Article Nutrition & Dietetics

Hydro-Ethanolic Fruit Extract of Capsicum frutescens Reversed Triton-X-100-Induced Hyperlipidaemia in Rats

Nurudeen S. Adigun et al.

JOURNAL OF DIETARY SUPPLEMENTS (2020)

Add to Collection

Article Gastroenterology & Hepatology

Gut commensal Parabacteroides goldsteinii plays a predominant role in the anti-obesity effects of polysaccharides isolated from Hirsutella sinensis

Tsung-Ru Wu et al.

GUT (2019)

Add to Collection

Article Food Science & Technology

Polysaccharide peptides from Ganoderma lucidum ameliorate lipid metabolic disorders and gut microbiota dysbiosis in high-fat diet-fed rats

Xu-Cong Lv et al.

JOURNAL OF FUNCTIONAL FOODS (2019)

Add to Collection

Review Medicine, General & Internal

The epidemiological burden of obesity in childhood: a worldwide epidemic requiring urgent action

Mariachiara Di Cesare et al.

BMC MEDICINE (2019)

Add to Collection

Review Veterinary Sciences

The Gastrointestinal Microbiome: A Review

P. C. Barko et al.

JOURNAL OF VETERINARY INTERNAL MEDICINE (2018)

Add to Collection

Article Agricultural Engineering

Chemical characterization and free radical scavenging capacity of oils obtained from Torreya grandis Fort. ex. Lindl. and Torreya grandis Fort. var. Merrillii: A comparative study using chemometrics

Long-Kai Shi et al.

INDUSTRIAL CROPS AND PRODUCTS (2018)

Add to Collection

Article Microbiology

Modulation of Active Gut Microbiota by Lactobacillus rhamnosus GG in a Diet Induced Obesity Murine Model

Yosep Ji et al.

FRONTIERS IN MICROBIOLOGY (2018)

Add to Collection

Article Microbiology

The Lactobacillus Bile Salt Hydrolase Repertoire Reveals Niche-Specific Adaptation

Sarah O'Flaherty et al.

MSPHERE (2018)

Add to Collection

Article Multidisciplinary Sciences

Mucosal microbiota of intestinal polyps reveals putative biomarkers of colorectal cancer

Marta Mangifesta et al.

SCIENTIFIC REPORTS (2018)

Add to Collection

Article Biochemistry & Molecular Biology

A combination of quercetin and resveratrol reduces obesity in high-fat diet-fed rats by modulation of gut microbiota

Le Zhao et al.

FOOD & FUNCTION (2017)

Add to Collection

Review Microbiology

The Human Microbiome and Obesity: Moving beyond Associations

Padma Maruvada et al.

CELL HOST & MICROBE (2017)

Add to Collection

Article Biochemistry & Molecular Biology

Anti-obese effects of two Lactobacilli and two Bifidobacteria on ICR mice fed on a high fat diet

Zhipeng Li et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)

Add to Collection

Review Biochemistry & Molecular Biology

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

Ara Koh et al.

CELL (2016)

Add to Collection

Article Chemistry, Applied

Chemical components of cold pressed kernel oils from different Torreya grandis cultivars

Zhiyong He et al.

FOOD CHEMISTRY (2016)

Add to Collection

Letter Gastroenterology & Hepatology

Obesity and colorectal cancer risk: the role of oxidative stress

Alphons J. M. Vermorken et al.

GUT (2014)

Add to Collection

Article Chemistry, Applied

Supercritical Carbon Dioxide Extraction, Fatty Acid Composition, Oxidative Stability, and Antioxidant Effect of Torreya grandis Seed Oil

Didi Dong et al.

JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY (2014)

Add to Collection

Review Biochemistry & Molecular Biology

The gut microbiota, obesity and insulin resistance

Jian Shen et al.

MOLECULAR ASPECTS OF MEDICINE (2013)

Add to Collection

Article Biochemistry & Molecular Biology

Effects of Japanese torreya (Torreya nucifera) seed oil on the activities and mRNA expression of lipid metabolism-related enzymes in rats

Yasushi Endo et al.

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2007)

Add to Collection

Article Biochemistry & Molecular Biology

Metabolic characterization of sciadonic acid (5c,11c,14c-eicosatrienoic acid) as an effective substitute for arachidonate of phosphatidylinositol

T Tanaka et al.

EUROPEAN JOURNAL OF BIOCHEMISTRY (2001)

Add to Collection

© Peeref 2019-2024. All rights reserved.