Persistent organic pollutants in hospitalized individuals in the municipality of Petropolis, Brazil

Persistent organic pollutants (POPs) are highly lipophilic and can accumulate and biomagnify in food chains. Characterized as a public health problem, exposure to these compounds enables the development of diseases like cancer, cardiovascular disease, diabetes, and obesity. The objective of this study was to estimate the plasma levels of organochlorine pesticides and PCBs in 151 samples (97 women; 54 men) in hospitalized individuals in Petropolis, Brazil. Individuals over 18 years of age and residing for at least 2 years in the mountainous region of the State of Rio de Janeiro, Brazil, participated in a cross-sectional study. Interviews using a structured questionnaire and blood samples to estimate plasma levels of persistent organic pollutants provided data. Gas chromatography coupled with triple quadrupole mass spectrometry provided the levels of organochlorine pesticides and PCBs. Compared to data present in the literature, the concentration of POPs was lower, and individuals from 55 to 64 years of age (3.28 ng mL(-1)) and women (2.52 ng mL(-1)) presented a higher average concentration of organochlorine pesticides; men (0.05 ng mL(-1)) also presented a high concentration of PCBs. This is the first Brazilian study to estimate the concentration of several POPs in a hospital-based sample that includes men and women, thus contributing to the characterization of our population regarding environmental exposures relevant to health.

Automated summary

The objective of this study was to estimate the plasma levels of organochlorine pesticides and PCBs in hospitalized individuals in Petropolis, Brazil. Compared to data present in the literature, the concentration of POPs was lower, and individuals from 55 to 64 years of age and women presented a higher average concentration of organochlorine pesticides; men also presented a high concentration of PCBs.