4.6 Article

An Efficient Transfer and Ensemble Learning Based Computer Aided Breast Abnormality Diagnosis System

Journal

IEEE ACCESS
Volume 11, Issue -, Pages 21199-21209

Publisher

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/ACCESS.2022.3192857

Keywords

Feature extraction; Solid modeling; Mammography; Deep learning; Pathology; Medical diagnostic imaging; Delta-sigma modulation; Mammogram classification; breast cancer; medical imaging; computer-aided diagnosis (CADx)

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Breast cancer is the second most deadly cancer among women, but can be prevented through early detection. Researchers have developed Computer-Aided Diagnosis (CADx) systems, with the use of Deep Learning and Convolutional Neural Networks (CNNs) revolutionizing their development. By integrating the state-of-the-art pre-trained model EfficientNet with other models and applying ensemble learning, significant improvements in accuracy have been achieved.
Breast cancer is the second most deadly type of cancer globally among women and can be prevented to a great extent in the case of early detection. In order to raise the survival rate, research scientists have conducted several experiments to develop tools to alleviate this problem, including Computer-Aided Diagnosis (CADx) systems. Deep Learning and its important sub-field Convolutional Neural Networks (CNN)s have revolutionized (CADx) development research. While the Curated Breast Imaging Subset of Digital Database for Screening Mammography, or the CBIS-DDSM dataset, has been classified using different pre-trained architectures, few of them have used ensemble learning to provide a more robust and accurate architecture. To the best of our knowledge, we are the first to integrate the application of the state-of-the-art pre-trained model called EfficientNet along with other pre-trained models for the part, and subsequently, the models were concatenated (ensembled). With the application of pre-trained CNN-based models, we are able to address the problem of not having a large dataset. Nevertheless, with the EfficientNet family offering better results with fewer parameters, we obtained significant improvement in accuracy, and later ensemble learning was applied to provide robustness for the network. After performing 10-fold cross-validation, our experiments yielded promising test accuracy results, 96.05% and 85.71% for abnormality type and pathology diagnosis classification, respectively.

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