Journal
CLINICS IN CHEST MEDICINE
Volume 36, Issue 1, Pages 67-78Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.ccm.2014.10.004
Keywords
Mycobacterium abscessus; Mycobacterium massiliense; Antimicrobial therapy; NTM lung diseases; Antimicrobial resistance; Drug susceptibility testing; Surgical therapy
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Rapidly growing mycobacteria (RGM) include a diverse group of species. We address the treatment of the most commonly isolated RGM - M abscessus complex, M fortuitum, and M chelonae. The M abscessus complex is composed of 3 closely related species: M abscessus senso stricto (hereafter M abscessus), M massiliense, and M bolletii. Most studies address treatment of M abscessus complex, which accounts for 80% of lung disease caused by RGM and is the second most common RGM to cause extrapulmonary disease (after M fortuitum). The M abscessus complex represent the most drug-resistant nontuberculous nnycobacteria and are the most difficult to treat.
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