Related references
Note: Only part of the references are listed.PI3K drives the de novo synthesis of coenzyme A from vitamin B5
Christian C. Dibble et al.
NATURE (2022)
Extracellular vesicles promote epithelial-to-mesenchymal transition of lens epithelial cells under oxidative stress
Ruixin Wang et al.
EXPERIMENTAL CELL RESEARCH (2021)
NLRP3 Deficiency Attenuates Secondary Degeneration of Visual Cortical Neurons Following Optic Nerve Injury
Zhou Zhang et al.
NEUROSCIENCE BULLETIN (2020)
Metabolic switch and epithelial-mesenchymal transition cooperate to regulate pluripotency
Hao Sun et al.
EMBO JOURNAL (2020)
Comparative analysis of the mitochondrial morphology, energy metabolism, and gene expression signatures in three types of blastocyst-derived stem cells
Joonhyuk Choi et al.
REDOX BIOLOGY (2020)
EGF promotes DKK1 transcription in hepatocellular carcinoma by enhancing the phosphorylation and acetylation of histone H3
Jie Niu et al.
SCIENCE SIGNALING (2020)
Human pantothenate kinase 4 is a pseudo-pantothenate kinase
Jiangwei Yao et al.
PROTEIN SCIENCE (2019)
Prognostic significance of the PANK family expression in acute myeloid leukemia
Yan Liu et al.
ANNALS OF TRANSLATIONAL MEDICINE (2019)
Enhanced EGF receptor-signaling potentiates TGFβ-induced lens epithelial-mesenchymal transition
Daisy Y. Shu et al.
EXPERIMENTAL EYE RESEARCH (2019)
ERK1/2-mediated EGFR-signaling is required for TGF beta-induced lens epithelial-mesenchymal transition
Daisy Y. Shu et al.
EXPERIMENTAL EYE RESEARCH (2019)
A novel mutation of PANK4 causes autosomal dominant congenital posterior cataract
Min Sun et al.
HUMAN MUTATION (2019)
Oncogenic Kinase-Induced PKM2 Tyrosine 105 Phosphorylation Converts Nononcogenic PKM2 to a Tumor Promoter and Induces Cancer Stem-like Cells
Zhifen Zhou et al.
CANCER RESEARCH (2018)
Deletion of GLUT1 in mouse lens epithelium leads to cataract formation
Aditi Swarup et al.
EXPERIMENTAL EYE RESEARCH (2018)
Low-Intensity Pulsed Ultrasound Protects Retinal Ganglion Cell From Optic Nerve Injury Induced Apoptosis via Yes Associated Protein
Jia-Xing Zhou et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2018)
PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis
Fabao Liu et al.
NATURE CELL BIOLOGY (2017)
Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction
Weier Qi et al.
NATURE MEDICINE (2017)
MicroRNA-26a and-26b inhibit lens fibrosis and cataract by negatively regulating Jagged-1/Notch signaling pathway
Xiaoyun Chen et al.
CELL DEATH AND DIFFERENTIATION (2017)
PKM2 Promotes Cell Survival and Invasion Under Metabolic Stress by Enhancing Warburg Effect in Pancreatic Ductal Adenocarcinoma
Chenggang Li et al.
DIGESTIVE DISEASES AND SCIENCES (2016)
AGEs in human lens capsule promote the TGF2-mediated EMT of lens epithelial cells: implications for age-associated fibrosis
Cibin T. Raghavan et al.
AGING CELL (2016)
Statin use and risk of cataract: A nested case-control study within a healthcare database
Manuela Casula et al.
ATHEROSCLEROSIS (2016)
A family of metal-dependent phosphatases implicated in metabolite damage-control
Lili Huang et al.
NATURE CHEMICAL BIOLOGY (2016)
PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation
Min Xie et al.
NATURE COMMUNICATIONS (2016)
PKM2 dephosphorylation by Cdc25A promotes the Warburg effect and tumorigenesis
Ji Liang et al.
NATURE COMMUNICATIONS (2016)
Endothelial to Mesenchymal Transition (EndoMT) in the Pathogenesis of Human Fibrotic Diseases
Sonsoles Piera-Velazquez et al.
JOURNAL OF CLINICAL MEDICINE (2016)
Pyruvate kinase: Function, regulation and role in cancer
William J. Israelsen et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2015)
Statins and Cataracts-a Visual Insight
Jeanne M. Dobrzynski et al.
CURRENT ATHEROSCLEROSIS REPORTS (2015)
PKM2 Isoform-Specific Deletion Reveals a Differential Requirement for Pyruvate Kinase in Tumor Cells
William J. Israelsen et al.
CELL (2013)
The epigenetic modifier trichostatin A, a histone deacetylase inhibitor, suppresses proliferation and epithelial-mesenchymal transition of lens epithelial cells
X. Chen et al.
CELL DEATH & DISEASE (2013)
Association of Statin Use With Cataracts A Propensity Score-Matched Analysis
Jessica Leuschen et al.
JAMA OPHTHALMOLOGY (2013)
PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis
Weiwei Yang et al.
CELL (2012)
Pyruvate Kinase M2 Regulates Gene Transcription by Acting as a Protein Kinase
Xueliang Gao et al.
MOLECULAR CELL (2012)
ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect
Weiwei Yang et al.
NATURE CELL BIOLOGY (2012)
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
Weibo Luo et al.
CELL (2011)
Aldose reductase-mediated induction of epithelium-to-mesenchymal transition (EMT) in lens
Gregory J. Zablocki et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2011)
Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation
Weiwei Yang et al.
NATURE (2011)
The lens as a model for fibrotic disease
J. A. Eldred et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2011)
Homeostasis in the vertebrate lens: mechanisms of solute exchange
Ralf Dahm et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2011)
Understanding the role of growth factors in embryonic development: insights from the lens
F. J. Lovicu et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2011)
HIF-1: upstream and downstream of cancer metabolism
Gregg L. Semenza
CURRENT OPINION IN GENETICS & DEVELOPMENT (2010)
Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth
Taro Hitosugi et al.
SCIENCE SIGNALING (2009)
Prevention of Posterior Capsular Opacification through Aldose Reductase Inhibition
Umesh C. S. Yadav et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2009)
Pyruvate kinase M2 is a phosphotyrosine-binding protein
Heather R. Christofk et al.
NATURE (2008)
Fibrotic disorders in the eye: Targets of gene therapy
Shizuya Saika et al.
PROGRESS IN RETINAL AND EYE RESEARCH (2008)
PanK4 inhibits pancreatic β-cell apoptosis by decreasing the transcriptional level of pro-caspase-9
Ruo Lan Xiang et al.
CELL RESEARCH (2007)
Crystal structures of human pantothenate kinases - Insights into allosteric regulation and mutations linked to a neurodegeneration disordew
Bum Soo Hong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Chemical knockout of pantothenate kinase reveals the metabolic and genetic program responsible for hepatic coenzyme a homeostasis
Yong-Mei Zhang et al.
CHEMISTRY & BIOLOGY (2007)
Plant coenzyme A biosynthesis:: characterization of two pantothenate kinases from Arabidopsis
G. B. Tilton et al.
PLANT MOLECULAR BIOLOGY (2006)
The epithelial-mesenchymal transition: new insights in signaling, development, and disease
JM Lee et al.
JOURNAL OF CELL BIOLOGY (2006)
Smad3 is key to TGF-β-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis
AB Roberts et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2006)
High glucose upregulates pantothenate kinase 4 (PanK4) and thus affects M2-type pyruvate kinase (Pkm2)
YF Li et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2005)
Relationship between posterior capsule opacification and intraocular lens biocompatibility
S Saika
PROGRESS IN RETINAL AND EYE RESEARCH (2004)
Epithelial-mesenchymal transition and its implications for fibrosis
R Kalluri et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Epithelial transdifferentiation and cataract in the human lens
JM Marcantonio et al.
EXPERIMENTAL EYE RESEARCH (2003)
An isoform of hPANK2, deficient in pantothenate kinase-associated neurodegeneration, localizes to mitochondria
K Hörtnagel et al.
HUMAN MOLECULAR GENETICS (2003)
Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family
KS Hewitson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Posterior capsule opacification: A cell biological perspective
IM Wormstone
EXPERIMENTAL EYE RESEARCH (2002)
A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome
B Zhou et al.
NATURE GENETICS (2001)