4.8 Article

Specification, stochastic modeling and analysis of interactive service robotic applications

Journal

ORGANIC LETTERS
Volume 25, Issue 9, Pages 1569-1572

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.3c004151569Org

Keywords

-

Ask authors/readers for more resources

N-Trifluoroacetylated sulfoximines react with 1-trifluoromethylstyrenes in a one-pot domino reaction to give fluorinated 5,6-dihydro-1,2-thiazine 1-oxides in good to high yields. The reaction involves nucleophilic allylic substitution, hydrolysis, and intramolecular nucleophilic vinylic substitution. The resulting product's molecular structure was confirmed by X-ray crystallographic analysis.
N-Trifluoroacetylated (N-TFA) sulfoximines react with 1-trifluoromethylstyrenes in a one-pot domino reaction to give fluorinated 5,6-dihydro-1,2-thiazine 1-oxides in good to high yields. The process involves three sequential reaction steps that can be characterized as (1) nucleophilic allylic substitution (SN2 '), (2) hydrolysis, and (3) intramolecular nucleophilic vinylic substitution (SNV). The products can further be modified by defluorination. The molecular structure of the resulting product was confirmed by X-ray crystallographic analysis.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.8
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available