Microvascular decompression for young onset primary trigeminal neuralgia: a single-center experience

This study aims to explore the causes of primary young onset trigeminal neuralgia (TN) and the clinical outcomes of these patients. From May 2015 to December 2020, 19 primary TN patients with onset age under 30 years underwent microvascular decompression (MVD) in Nanjing Drum Tower Hospital. In this study, the clinical characteristics, surgical outcomes, and postoperative complications of these patients were analyzed retrospectively. Of the 19 patients, 5 were males and 14 were females, and the pain was located on the right side in 10 cases (52.6%). Vascular compression was observed in 17 patients, including 14 cases of superior cerebellar artery (SCA) alone, 2 cases of superior petrosal vein (SPV) alone, and 1 case of SCA and SPV combined. Two patients had no neurovascular conflict, and nerve combing was performed. After surgery, 18 patients got immediate pain relief; 1 patient improved but still had occasional pain. With a mean follow-up of 42.7 +/- 22.3 months, one patient was found to have a relapse 45 months after MVD. Surgical complications including mild facial numbness in two patients and hearing impairment in one patient. Neurovascular compression is the main cause of young onset primary TN, and the most commonly encountered vascular was SCA. MVD is a safe and effective treatment for these patients.

Automated summary

This study aimed to investigate the causes and clinical outcomes of primary young onset trigeminal neuralgia (TN). The study retrospectively analyzed the clinical characteristics, surgical outcomes, and postoperative complications of 19 primary TN patients who underwent microvascular decompression (MVD) at Nanjing Drum Tower Hospital. The results showed that neurovascular compression, especially by the superior cerebellar artery, was the main cause of primary young onset TN. MVD was a safe and effective treatment for these patients.