☆ 4.4 Review

Advances in Catalytic Asymmetric Reactions Involving o-Hydroxybenzyl Alcohols

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A Strategy for Synthesizing Axially Chiral Naphthyl-Indoles: Catalytic Asymmetric Addition Reactions of Racemic Substrates

Fei Jiang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

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Article Chemistry, Organic

Asymmetric Synthesis of Triaryl-Substituted Chromans with Multiple Stereogenic Centers by [4+2] Cycloaddition Reaction

Heng Zhang et al.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2019)

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Diastereo- and Atroposelective Synthesis of Bridged Biaryls Bearing an Eight-Membered Lactone through an Organocatalytic Cascade

Shenci Lu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

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Design and Catalytic Asymmetric Construction of Axially Chiral 3,3′-Bisindole Skeletons

Chun Ma et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

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Review Chemistry, Organic

Enantioselective Synthesis of Atropisomers Featuring Pentatomic Heteroaromatics

Shuo Zhang et al.

CHINESE JOURNAL OF ORGANIC CHEMISTRY (2019)

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Conversion of two stereocenters to one or two chiral axes: atroposelective synthesis of 2,3-diarylbenzoindoles

Yu-Long Hu et al.

CHEMICAL SCIENCE (2019)

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Recent advances in the synthesis of axially chiral biaryls via transition metal-catalysed asymmetric C-H functionalization

Gang Liao et al.

CHEMICAL COMMUNICATIONS (2019)

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Organocatalytic asymmetric arylation of indoles enabled by azo groups

Liang-Wen Qi et al.

NATURE CHEMISTRY (2018)

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Construction of Axially Chiral Compounds via Asymmetric Organocatalysis

Yong-Bin Wang et al.

ACCOUNTS OF CHEMICAL RESEARCH (2018)

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Mannich base-connected syntheses mediated by ortho-quinone methides

Petra Barta et al.

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY (2018)

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Catalytic asymmetric synthesis of spirooxindoles: recent developments

Guang-Jian Mei et al.

CHEMICAL COMMUNICATIONS (2018)

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Recent advances in the application of Diels-Alder reactions involving o-quinodimethanes, aza-o-quinone methides and o-quinone methides in natural product total synthesis

Baochao Yang et al.

CHEMICAL SOCIETY REVIEWS (2018)

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Organocatalytic Enantioselective Synthesis of Chiral Diarylmethylamines from Racemic Alcohols

Min Chen et al.

CHINESE JOURNAL OF CHEMISTRY (2018)

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A Bird's Eye View of Atropisomers Featuring a Five-Membered Ring

Damien Bonne et al.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2018)

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Enantioselective Decarboxylative Alkylation of beta-Keto Acids to ortho-Quinone Methides as Reactive Intermediates: Asymmetric Synthesis of 2,4-Diaryl-1-benzopyrans

Hyun Jung Jeong et al.

ORGANIC LETTERS (2018)

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Phosphoric Acid Catalyzed Aldehyde Addition to in Situ Generated o-Quinone Methides: An Enantio- and Diastereoselective Entry toward cis-3,4-Diaryl Dihydrocoumarins

Matthias Spanka et al.

ORGANIC LETTERS (2018)

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Palladium-Catalyzed Enantioselective Addition of Chiral Metal Enolates to In Situ Generated ortho-Quinone Methides

Fabian Goericke et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

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Phosphoric Acid Catalyzed [4+1]-Cycloannulation Reaction of ortho-Quinone Methides and Diazoketones: Catalytic, Enantioselective Access toward cis-2,3-Dihydrobenzofurans

Arun Suneja et al.

ORGANIC LETTERS (2018)

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Design and Enantioselective Construction of Axially Chiral Naphthyl-Indole Skeletons

Hong-Hao Zhang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

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Indolylmethanols as Reactants in Catalytic Asymmetric Reactions

Guang-Jian Mei et al.

JOURNAL OF ORGANIC CHEMISTRY (2017)

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Chiral phosphoric acid catalyzed enantioselective annulation of acyclic enecarbamates to in situ-generated ortho-quinone methides

Chandan Gharui et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2017)

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Catalytic Asymmetric Total Synthesis of (+)- and (-)-Paeoveitol via a Hetero-Diels-Alder Reaction

Tian-Ze Li et al.

ORGANIC LETTERS (2017)

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Enantioselective [4+2] Cycloaddition of o-Quinone Methides and Vinyl Sulfides: Indirect Access to Generally Substituted Chiral Chromanes

Zhaobin Wang et al.

ORGANIC LETTERS (2017)

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ortho-Quinone methides as key intermediates in cascade heterocyclizations

Dmitry V. Osipov et al.

RUSSIAN CHEMICAL REVIEWS (2017)

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Catalytic asymmetric substitution of ortho-hydroxybenzyl alcohols with tetronic acid-derived enamines: enantioselective synthesis of tetronic acid-derived diarylmethanes

Meng-Meng Xu et al.

ORGANIC CHEMISTRY FRONTIERS (2017)

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Catalytic asymmetric C2-nucleophilic substitutions of C3-substituted indoles with ortho-hydroxybenzyl alcohols

Jia-Le Wu et al.

ORGANIC CHEMISTRY FRONTIERS (2017)

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Enantioselective syntheses of atropisomers featuring a five-membered ring

Damien Bonne et al.

CHEMICAL COMMUNICATIONS (2017)

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Enantioselective Addition of Thiols to ortho-Quinone Methides Catalyzed by Chiral Phosphoric Acids

Zengwei Lai et al.

SYNLETT (2016)

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Catalytic Asymmetric [4+2] Cycloaddition of o-Hydroxybenzyl Alcohols with o-Hydroxyl Styrenes: Diastereo- and Enantioselective Construction of Chiral Chroman Scaffold

Wu Qiong et al.

ACTA CHIMICA SINICA (2016)

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Synergistic Rhodium/Phosphoric Acid Catalysis for the Enantioselective Addition of Oxonium Ylides to ortho-Quinone Methides

Santosh Kumar Alamsetti et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

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Catalytic Asymmetric Cycloaddition of In Situ-Generated ortho-Quinone Methides and Azlactones by a Triple BrOnsted Acid Activation Strategy

Xiao-Ye Yu et al.

CHEMISTRY-A EUROPEAN JOURNAL (2016)

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Chiral N,N′-Dioxide-Scandium(III) Complex-Catalyzed Asymmetric Friedel-Crafts Alkylation Reaction of ortho-Hydroxybenzyl Alcohols with C3-Substituted N-Protected Indoles

Jianfeng Zheng et al.

CHEMISTRY-A EUROPEAN JOURNAL (2016)

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Merging Chiral Bronsted Acid/Base Catalysis: An Enantioselective [4+2] Cycloaddition of o-Hydroxystyrenes with Azlactones

Yu-Chen Zhang et al.

JOURNAL OF ORGANIC CHEMISTRY (2016)

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Emerging Roles of in Situ Generated Quinone Methides in-Metal-Free Catalysis

Ashley A. Jaworski et al.

JOURNAL OF ORGANIC CHEMISTRY (2016)

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Design and Application of 3-Alkyl-2-vinylindoles in BrOnsted Acid Catalyzed Reactions

Guang-Jian Mei et al.

SYNLETT (2016)

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Chiral Bronsted acid-catalyzed alkylation of C3-substituted indoles with o-hydroxybenzyl alcohols: highly enantioselective synthesis of diarylindol-2-ylmethanes and evaluation on their cytotoxicity

Qiong Wu et al.

TETRAHEDRON-ASYMMETRY (2016)

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Ortho-Quinone Methides as Reactive Intermediates in Asymmetric Bronsted Acid Catalyzed Cycloadditions with Unactivated Alkenes by Exclusive Activation of the Electrophile

Chien-Chi Hsiao et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

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Catalytic Asymmetric Inverse-Electron-Demand Oxa-Diels-Alder Reaction of In Situ Generated ortho-Quinone Methides with 3-Methyl-2-Vinylindoles

Jia-Jia Zhao et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

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Chiral Bronsted acid-catalyzed Friedel-Crafts alkylation of electron-rich arenes with in situ-generated ortho-quinone methides: highly enantioselective synthesis of diarylindolylmethanes and triarylmethanes

Satyajit Saha et al.

CHEMICAL COMMUNICATIONS (2015)

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Applications of ortho-Quinone Methides in the Synthesis of Natural Products

Wenying Ai et al.

CHINESE JOURNAL OF ORGANIC CHEMISTRY (2015)

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Catalytic Chemo-, E/Z-, and Enantioselective Cyclizations of o-Hydroxybenzyl Alcohols with Dimedone-Derived Enaminones

Jia-Jia Zhao et al.

JOURNAL OF ORGANIC CHEMISTRY (2015)

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The Emergence of Quinone Methides in Asymmetric Organocatalysis

Lorenzo Caruana et al.

MOLECULES (2015)

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Organocatalytic Asymmetric Nucleophilic Addition to o-Quinone Methides by Alcohols

Zengwei Lai et al.

ORGANIC LETTERS (2015)

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Directing Group Assisted Nucleophilic Substitution of Propargylic Alcohols via o-Quinone Methide Intermediates: Bronsted Acid Catalyzed, Highly Enantio- and Diastereoselective Synthesis of 7-Alkynyl-12a-acetamido-Substituted Benzoxanthenes

Satyajit Saha et al.

ORGANIC LETTERS (2015)

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Recent Advances in Catalytic Asymmetric Reactions of o-Quinone Methides

Zhaobin Wang et al.

SYNTHESIS-STUTTGART (2015)

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Enantioselective Formation of All-Carbon Quaternary Stereocenters from Indoles and Tertiary Alcohols Bearing A Directing Group

Wanxiang Zhao et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

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Bronsted Acid-Catalyzed, Highly Enantioselective Addition of Enamides to In Situ-Generated ortho-Quinone Methides: A Domino Approach to Complex Acetamidotetrahydroxanthenes

Satyajit Saha et al.

CHEMISTRY-A EUROPEAN JOURNAL (2015)

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The Domestication of ortho-Quinone Methides

Wen-Ju Bai et al.

ACCOUNTS OF CHEMICAL RESEARCH (2014)

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Asymmetric Organocatalysis Combined with Metal Catalysis: Concept, Proof of Concept, and Beyond

Dian-Feng Chen et al.

ACCOUNTS OF CHEMICAL RESEARCH (2014)

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Enantio- and Diastereoselective Access to Distant Stereocenters Embedded within Tetrahydroxanthenes: Utilizing ortho-Quinone Methides as Reactive Intermediates in Asymmetric Bronsted Acid Catalysis

Chien-Chi Hsiao et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)

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Bronsted Acid Catalyzed, Conjugate Addition of β-Dicarbonyls to In Situ Generated ortho-Quinone Methides-Enantioselective Synthesis of 4-Aryl-4H-Chromenes

Osama El-Sepelgy et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)

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Review Chemistry, Multidisciplinary

ortho-Quinone methide (o-QM): a highly reactive, ephemeral and versatile intermediate in organic synthesis

Maya Shankar Singh et al.

RSC ADVANCES (2014)

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Review Chemistry, Multidisciplinary

ortho-Quinone Methides in Natural Product Synthesis

Nicky J. Willis et al.

CHEMISTRY-A EUROPEAN JOURNAL (2012)

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Applications of ortho-Quinone Methide Intermediates in Catalysis and Asymmetric Synthesis

Tejas P. Pathak et al.

JOURNAL OF ORGANIC CHEMISTRY (2011)

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Chiral Organic Contact Ion Pairs in Metal-Free Catalytic Asymmetric Allylic Substitutions

Magnus Rueping et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

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Enantioselective Bronsted Acid Catalysis in the Friedel-Crafts Reaction of Indoles with Secondary ortho-Hydroxybenzylic Alcohols

David Wilcke et al.

SYNLETT (2011)

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Aryne, ortho-Quinone Methide, and ortho-Quinodimethane: Synthesis of Multisubstituted Arenes Using the Aromatic Reactive Intermediates

Hiroto Yoshida et al.

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN (2010)

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Syntheses of Chromenes and Chromanes via o-Quinone Methide Intermediates

Sabrina B. Ferreira et al.

JOURNAL OF HETEROCYCLIC CHEMISTRY (2009)

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o-quinone methides:: intermediates underdeveloped and underutilized in organic synthesis

RW Van de Water et al.

TETRAHEDRON (2002)

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