4.5 Article

ParticleChromo3D+: A Web Server for ParticleChromo3D Algorithm for 3D Chromosome Structure Reconstruction

Journal

CURRENT ISSUES IN MOLECULAR BIOLOGY
Volume 45, Issue 3, Pages 2549-2560

Publisher

MDPI
DOI: 10.3390/cimb45030167

Keywords

Hi-C; 3D chromosome structure; chromosome conformation capture; 3D genome

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ParticleChromo3D+ is a containerized web-based genome structure reconstruction server/tool, which provides researchers with a portable and accurate tool for analyses via a graphical user interface (GUI). It saves time for researchers, eases usage pain points, and offloads computational processing/installation time.
Understanding the three-dimensional (3D) structure of chromatin is invaluable for researching how it functions. One way to gather this information is the chromosome conformation capture (3C) technique and its follow-up technique Hi-C. Here, we present ParticleChromo3D+, a containerized web-based genome structure reconstruction server/tool that provides researchers with a portable and accurate tool for analyses. Additionally, ParticleChromo3D+ provides a more user-friendly way to access its capabilities via a graphical user interface (GUI). ParticleChromo3D+ can save time for researchers by increasing the accessibility of genome reconstruction, easing usage pain points, and offloading computational processing/installation time.

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