Journal
CHEMICAL SCIENCE
Volume 14, Issue 16, Pages 4230-4247Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d3sc00992k
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Flow chemistry has revolutionized synthetic community by providing numerous possibilities. This review explores the benefits of microreactor technology and how it can enhance organic synthesis by revealing governing principles and unique reactivity. It serves as a field guide for those interested in diving into the world of flow chemistry.
Flow chemistry has unlocked a world of possibilities for the synthetic community, but the idea that it is a mysterious black box needs to go. In this review, we show that several of the benefits of microreactor technology can be exploited to push the boundaries in organic synthesis and to unleash unique reactivity and selectivity. By lifting the veil on some of the governing principles behind the observed trends, we hope that this review will serve as a useful field guide for those interested in diving into flow chemistry.
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