Administration methods of lipid-based nanoparticle delivery systems for cancer treatment

As nano medications have developed in the recent four decades, nano-delivery systems have been applied in treating various diseases and are especially common in cancer treatment. Nano-delivery systems could target cancer-associated cells, enhance the accuracy and efficacy of treatment, and reduce systemic side effects. Among the many drugs on nano-carriers, the load system of lipid-based nanoparticles has the brightest prospect due to the high level of biocompatibility, biodegradability, loading capability, and immunogenicity. Previous reviews have comprehensively introduced their effects and progress. However, most of them did not provide great attention to practical applications. This article will focus on different intake methods, which decide the biological process of drugs. This suggests that we can modify lipid-based nano-delivery systems according to how they are capable of prolonging the half-life span and magnifying therapy effects in treating cancer. Besides, we put forth the problems that should be further studied in the future and their probable solutions.

Automated summary

As nano medications have advanced in the last four decades, nano-delivery systems have been used in the treatment of various diseases, particularly in cancer treatment. These systems can target cancer cells, improve treatment accuracy and effectiveness, and reduce systemic side effects. Among lipid-based nanoparticles, the load system shows great promise due to its high biocompatibility, biodegradability, loading capability, and immunogenicity. While previous reviews have focused on their effects and progress, this article highlights the importance of practical applications, such as intake methods, in determining the biological process of drugs. It also discusses potential solutions to problems that need further study in the future.