Journal
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Volume 41, Issue 2, Pages 199-213Publisher
CLINICAL & EXPER RHEUMATOLOGY
Keywords
myositis; polymyositis; dermatomyositis; treatment; pathogenesis
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Idiopathic inflammatory myopathies (IIM) are a diverse group of disorders characterized by chronic inflammation of the skeletal muscle and muscle weakness. Different subtypes of IIM have been identified based on various factors such as extra-muscular manifestations, immunology, muscle histology, treatment response, and prognosis. This review focuses on the latest literature published in the past year regarding the pathogenesis, classification, treatment, and prognosis of different IIM subtypes.
Idiopathic inflammatory myopathies (IIM) are a heterogeneous group of disorders in which chronic inflamma-tion of the skeletal muscle, leading to muscle weakness, is a common feature. Different phenotypes have been identi-fied within the IIM spectrum based on extra-muscular manifestations, immu-nology, muscle histology, responsive-ness to therapy, and prognosis. The pathogenesis, classification, treatment, and prognosis of the different IIM sub-types are subject to active discussion and research. This review highlights the most relevant literature published on this topic over the last year.
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