Simultaneously controlling conformational and operational stability of single-chain polymeric nanoparticles in complex media

Single-chain polymeric nanoparticles (SCPNs) comprising a solvatochromic pyrazoline adduct show conformational and operational stability in complex media and in cellular compartments; the connectivity of the adduct is crucial in modulating interactions with the surrounding media.

Automated summary

Single-chain polymeric nanoparticles (SCPNs) containing solvatochromic pyrazoline adducts maintain conformational and operational stability in complex media and cellular compartments. The connectivity of the adduct plays a crucial role in modulating interactions with the surrounding media.