Co-catalysis of rhodium/phosphoramidite catalyst and ZSM-35(10) for the tandem hydroformylation-acetalization of olefins

The Rh/BINAPa and ZSM-35(10) co-catalyzed tandem hydroformylation-acetalization of olefins has been developed. A series of olefins with various alcohols performed well in the process, affording the corresponding acetals with high regioselectivities (l/b >= 30.5) and excellent catalytic activities (TON of the Rh catalyst up to 4.3 x 10(4)). Control experiments and DFT calculations indicated that the Rh/L11-catalyzed hydroformylation occurred in the solvent outside the molecular sieve, while the acetalization of intermediate aldehydes with alcohols takes place mainly in the interior of the molecular sieve.

Automated summary

The tandem hydroformylation-acetalization of olefins using Rh/BINAPa and ZSM-35(10) co-catalysts has been developed. Various olefins and alcohols showed high performance in terms of regioselectivity (l/b >= 30.5) and catalytic activity (TON of the Rh catalyst up to 4.3 x 10(4)). Control experiments and DFT calculations revealed that hydroformylation occurred outside the molecular sieve, while acetalization took place mainly inside the molecular sieve.