Journal
EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY
Volume 10, Issue 6, Pages 723-733Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1586/17474124.2016.1142872
Keywords
Gastroprotection; Non-steroidal anti-inflammatory drugs; COX-2 selective inhibitors; Low dose aspirin; Upper gastrointestinal complications; Cardiovascular risk; Gastrointestinal risk; Gastrointestinal bleeding; NSAID gastropathy
Categories
Ask authors/readers for more resources
Non-steroidal anti-inflammatory drug (NSAID) use increases the risk of gastrointestinal complications such as ulcers or bleeding. The presence of factors like advanced age, history of peptic ulcer, Helicobacter pylori infection and the use of anticoagulants or antiplatelet agents increase this risk further. COX-2 inhibitors and antisecretory drugs, particularly proton pump inhibitors, help to minimize the risk of gastrointestinal complications in high-risk patients. This review presents a practical approach to the prevention and treatment of NSAID-associated peptic ulcer disease and examines the new advances in the rational use of NSAIDs.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available