☆ 4.6 Article

Parallel evolution of cannabinoid biosynthesis

NATURE PLANTS (2023)

Related references

Note: Only part of the references are listed.

Review Plant Sciences

Cannabigerol: a bibliometric overview and review of research on an important phytocannabinoid

Chinedu P. Anokwuru et al.

Summary: CBG, a major phytocannabinoid in Cannabis sativa L., has diverse pharmacological properties, but there is a lack of clinical trials establishing its efficacy and safety, as well as industry-friendly quality control procedures for CBG-enriched cannabis extracts.

PHYTOCHEMISTRY REVIEWS (2022)

Add to Collection

Review Chemistry, Medicinal

Cannabidiol (CBD) From Non-Cannabis Plants: Myth or Reality?

Giovanni Appendino et al.

Summary: This article critically reviews reports on the occurrence of cannabidiol (CBD) in non-cannabis plants. The isolation of CBD from Humulus Kriya was found to be fraudulent, while its presence in Trema orientalis, stevia, and flax needs further confirmation. The concentration of cannabigerol (CBG) and its precursor (GBGA) in Helichrysum umbraculigerum could not be confirmed, but this plant deserves attention for possible phytocannabinoid accumulation.

NATURAL PRODUCT COMMUNICATIONS (2022)

Add to Collection

Review Pharmacology & Pharmacy

Cannabis for Medical Use: Versatile Plant Rather Than a Single Drug

Shiri Procaccia et al.

Summary: Medical cannabis and its major components THC and CBD are gaining popularity for various medical purposes, but studies regarding their efficacy are inconclusive due to the versatile nature of the cannabis plant and the interplay between its compounds and the endocannabinoid system.

FRONTIERS IN PHARMACOLOGY (2022)

Add to Collection

Article Biochemical Research Methods

Haplotype-resolved de novo assembly using phased assembly graphs with hifiasm

Haoyu Cheng et al.

Summary: hifiasm is a novel assembler that utilizes long high-fidelity sequence reads to accurately represent haplotype information, outperforming existing tools in haplotype-resolved assembly on various datasets, including a hexaploid genome dataset.

NATURE METHODS (2021)

Add to Collection

Article Multidisciplinary Sciences

Large-scale whole-genome resequencing unravels the domestication history of Cannabis sativa

Guangpeng Ren et al.

Summary: The study reveals the domestication history of Cannabis sativa, indicating that it was first domesticated in early Neolithic times in East Asia, and that both hemp and drug cultivars diverged from an ancestral gene pool in China. Candidate genes associated with traits differentiating hemp and drug cultivars were identified, as well as evidence for loss of function of genes involved in cannabinoid synthesis during selection.

SCIENCE ADVANCES (2021)

Add to Collection

Article Plant Sciences

Kingdom-wide analysis of the evolution of the plant type III polyketide synthase superfamily

Thomas Naake et al.

Summary: This study investigated the deep evolutionary history of the type III polyketide synthases (PKSs) by conducting phylogenomic synteny network and phylogenetic analyses. The results revealed that CHS and LAP5/6 homologs evolved early by segmental duplication prior to the divergence of Bryophytes and Tracheophytes. The macroevolution of the PKS superfamily was suggested to be governed by whole-genome duplications and triplications, with recent functional divergence captured by gene sequence alterations.

PLANT PHYSIOLOGY (2021)

Add to Collection

Review Pharmacology & Pharmacy

The Pharmacological Case for Cannabigerol

Rahul Nachnani et al.

Summary: Cannabigerol (CBG) is a unique phytocannabinoid with potential therapeutic properties in neurological, inflammatory bowel disease, and antibacterial activities. Despite its commercialization, limited research has been conducted on CBG, necessitating further exploration of its therapeutic uses and potential hazards.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2021)

Add to Collection

Article Biochemistry & Molecular Biology

Structure of the Cannabis sativa olivetol-producing enzyme reveals cyclization plasticity in type III polyketide synthases

Lewis J. Kearsey et al.

FEBS JOURNAL (2020)

Add to Collection

Review Biotechnology & Applied Microbiology

Plant Aromatic Prenyltransferases: Tools for Microbial Cell Factories

Wouter J. C. de Bruijn et al.

TRENDS IN BIOTECHNOLOGY (2020)

Add to Collection

Review Plant Sciences

Phytocannabinoids: Origins and Biosynthesis

Thies Gulck et al.

TRENDS IN PLANT SCIENCE (2020)

Add to Collection

Article Plant Sciences

Synthetic Biology of Cannabinoids and Cannabinoid Glucosides in Nicotiana benthamiana and Saccharomyces cerevisiae

Thies Gulck et al.

JOURNAL OF NATURAL PRODUCTS (2020)

Add to Collection

Article Biochemical Research Methods

Miso: an R package for multiple isotope labeling assisted metabolomics data analysis

Yonghui Dong et al.

BIOINFORMATICS (2019)

Add to Collection

Article Multidisciplinary Sciences

Complete biosynthesis of cannabinoids and their unnatural analogues in yeast

Xiaozhou Luo et al.

NATURE (2019)

Add to Collection

Article Biochemical Research Methods

Integrating Hi-C links with assembly graphs for chromosome-scale assembly

Jay Ghurye et al.

PLOS COMPUTATIONAL BIOLOGY (2019)

Add to Collection

Article Biotechnology & Applied Microbiology

OrthoFinder: phylogenetic orthology inference for comparative genomics

David M. Emms et al.

GENOME BIOLOGY (2019)

Add to Collection

Article Biotechnology & Applied Microbiology

Benchmarking transposable element annotation methods for creation of a streamlined, comprehensive pipeline

Shujun Ou et al.

GENOME BIOLOGY (2019)

Add to Collection

Article Biotechnology & Applied Microbiology

Subcellular localization defines modification and production of Δ9-tetrahydrocannabinolic acid synthase in transiently transformed Nicotiana benthamiana

Marcus Geissler et al.

BIOTECHNOLOGY LETTERS (2018)

Add to Collection

Article Biotechnology & Applied Microbiology

New Insights on Cyclization Specificity of Fungal Type III Polyketide Synthase, PKSIIINc in Neurospora crassa

Amreesh Parvez et al.

INDIAN JOURNAL OF MICROBIOLOGY (2018)

Add to Collection

Article Multidisciplinary Sciences

A new ESI-LC/MS approach for comprehensive metabolic profiling of phytocannabinoids in Cannabis

Paula Berman et al.

SCIENTIFIC REPORTS (2018)

Add to Collection

Article Chemistry, Medicinal

Amorfrutin-type phytocannabinoids from Helichrysum umbraculigerum

Federica Pollastro et al.

FITOTERAPIA (2017)

Add to Collection

Article Agronomy

The inheritance of chemical phenotype in Cannabis sativa L. (V): regulation of the propyl-/pentyl cannabinoid ratio, completion of a genetic model

E. P. M. de Meijer et al.

EUPHYTICA (2016)

Add to Collection

Review Biochemistry & Molecular Biology

Phytocannabinoids: a unified critical inventory

Lumir Ondrej Hanus et al.

NATURAL PRODUCT REPORTS (2016)

Add to Collection

Review Physiology

FROM PHYTOCANNABINOIDS TO CANNABINOID RECEPTORS AND ENDOCANNABINOIDS: PLEIOTROPIC PHYSIOLOGICAL AND PATHOLOGICAL ROLES THROUGH COMPLEX PHARMACOLOGY

Alessia Ligresti et al.

PHYSIOLOGICAL REVIEWS (2016)

Add to Collection

Article Plant Sciences

A Novel Class of Plant Type III Polyketide Synthase Involved in Orsellinic Acid Biosynthesis from Rhododendron dauricum

Futoshi Taura et al.

Frontiers in Plant Science (2016)

Add to Collection

Review Clinical Neurology

The Endocannabinoid System and its Modulation by Phytocannabinoids

Vincenzo Di Marzo et al.

NEUROTHERAPEUTICS (2015)

Add to Collection

Article Biology

Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species

Keith R. Bradnam et al.

GIGASCIENCE (2013)

Add to Collection

Article Multidisciplinary Sciences

Identification of olivetolic acid cyclase from Cannabis sativa reveals a unique catalytic route to plant polyketides

Steve J. Gagne et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Add to Collection

Article Biotechnology & Applied Microbiology

Differential phylogenetic expansions in BAHD acyltransferases across five angiosperm taxa and evidence of divergent expression among Populus paralogues

Lindsey K. Tuominen et al.

BMC GENOMICS (2011)

Add to Collection

Article Biochemistry & Molecular Biology

Characterization of olivetol synthase, a polyketide synthase putatively involved in cannabinoid biosynthetic pathway

Futoshi Taura et al.

FEBS LETTERS (2009)

Add to Collection

Review Plant Sciences

South African Helichrysum species: A review of the traditional uses, biological activity and phytochemistry

A. C. U. Lourens et al.

JOURNAL OF ETHNOPHARMACOLOGY (2008)

Add to Collection

Article Plant Sciences

Arabidopsis contains a large superfamily of acyl-activating enzymes. Phylogenetic and biochemical analysis reveals a new class of acyl-coenzyme A synthetases

JM Shockey et al.

PLANT PHYSIOLOGY (2003)

Add to Collection

Article Biochemistry & Molecular Biology

The activity of Arabidopsis glycosyltransferases toward salicylic acid, 4-hydroxybenzoic acid, and other benzoates

EK Lim et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Add to Collection

Article Biochemistry & Molecular Biology

Cloning and analysis of valerophenone synthase gene expressed specifically in lupulin gland of hop (Humulus lupulus L.)

Y Okada et al.

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2001)

Add to Collection

© Peeref 2019-2024. All rights reserved.