☆ 4.6 Article

In vivo and In vitro properties evaluation of curcumin loaded MgO doped 3D printed TCP scaffolds

JOURNAL OF MATERIALS CHEMISTRY B (2023)

Related references

Note: Only part of the references are listed.

Article Chemistry, Multidisciplinary

Raspberry-like gold nanozyme-hybrid liposomes for hypoxia-enhanced biofilm eradication

Lingyun Zou et al.

Summary: Bacterial biofilm-associated infection is a major threat to global public health due to antibiotic resistance. This study repurposes a hypoxia-activated anticancer drug, tirapazamine (TPZ), to treat biofilm-associated infections. A hypoxia-enhanced strategy is used to improve the efficacy of TPZ by encapsulating it into raspberry-like gold nanoparticle-hybrid liposomes (Lip@Au-TPZ). The gold nanoparticles act as nanozymes to catalyze glucose oxidation and aggravate biofilm hypoxia, leading to the eradication of biofilms.

NANO TODAY (2023)

Add to Collection

Article Engineering, Biomedical

3D printing of conch-like scaffolds for guiding cell migration and directional bone growth

Boshi Feng et al.

Summary: Inspired by the physiological features of conches, researchers successfully developed a conch-like scaffold using 3D printing technology. This scaffold, with its spiral structure, significantly improved cell adhesion, proliferation, and osteogenic differentiation. The scaffold efficiently guided cells to grow upward, and the capability of guiding directional bone growth was demonstrated in an animal model.

BIOACTIVE MATERIALS (2023)

Add to Collection

Article Chemistry, Multidisciplinary

Scaffold-Free Spheroids with Two-Dimensional Heteronano-Layers (2DHNL) Enabling Stem Cell and Osteogenic Factor Codelivery for Bone Repair

Xifeng Liu et al.

Summary: Functional spheroids engineered with two-dimensional heteronano-layers consisting of black phosphorus and graphene oxide show promising potential for bone tissue engineering. These spheroids successfully support osteogenesis of mesenchymal stem cells, neovascularization, and bone regeneration in vivo, as well as achieve outstanding in vivo osteogenic induction and bone regrowth without prior in vitro culture of osteogenic factor. The shortened overall culture time could be advantageous for clinical translation.

ACS NANO (2022)

Add to Collection

Article Nanoscience & Nanotechnology

Angiogenic Hyaluronic Acid Hydrogels with Curcumin-Coated Magnetic Nanoparticles for Tissue Repair

Radha Daya et al.

Summary: Angiogenic magnetic hydrogels were synthesized using magnetic nanoparticles (MNPs) with curcumin as an angiogenic agent. The CMNPs showed sustained release of curcumin and exhibited dose-dependent cytocompatibility when cultured with BMSCs. The magnetic hydrogels showed promising properties for tissue regeneration.

ACS APPLIED MATERIALS & INTERFACES (2022)

Add to Collection

Article Nanoscience & Nanotechnology

Ginger and Garlic Extracts Enhance Osteogenesis in 3D Printed Calcium Phosphate Bone Scaffolds with Bimodal Pore Distribution

Susmita Bose et al.

Summary: Ginger and garlic extracts have synergistic effects on osteogenesis and their osteogenic potential can be enhanced through drug release from bone scaffolds. Their release profiles fit the Weibull distribution equation, and they show good mechanical integrity. This research has important implications for bone tissue engineering and dental applications.

ACS APPLIED MATERIALS & INTERFACES (2022)

Add to Collection

Article Engineering, Biomedical

A biodegradable 3D woven magnesium-based scaffold for orthopedic implants

Ju Xue et al.

Summary: Porous Magnesium is a promising biodegradable scaffold for treating bone defects. It has shown sufficient biocompatibility and its mechanical properties are closer to cortical bone, reducing stress concentrations and shielding. 3D weaving with controlled chemistries and microstructures of Mg wires provides a new alternative to conventional additive techniques. The weaves are dip-coated with polylactic acid for enhanced strength and corrosion resistance.

BIOFABRICATION (2022)

Add to Collection

Article Multidisciplinary Sciences

A synthetic lipopeptide targeting top-priority multidrug-resistant Gram-negative pathogens

Kade D. Roberts et al.

Summary: The emergence of multidrug-resistant Gram-negative pathogens poses a global medical challenge. Polymyxin antibiotics are often the last therapeutic option against these pathogens, but they have limitations in safety and efficacy. This study reports the discovery and development of a synthetic lipopeptide that shows improved safety and efficacy against top-priority multidrug-resistant Gram-negative pathogens.

NATURE COMMUNICATIONS (2022)

Add to Collection

Article Materials Science, Multidisciplinary

Zinc curcumin complex on fluoride doped hydroxyapatite with enhanced biological properties for dental and orthopedic applications

Arjak Bhattacharjee et al.

Summary: This study utilizes a Zn2+-curcumin complex from a fluoride doped hydroxyapatite matrix to inhibit osteosarcoma, promote osteoblast growth, and provide antibacterial properties. The drug delivery system shows significant enhancement in cell viability and osteosarcoma inhibition, and exhibits antibacterial efficacy against Staphylococcus aureus. This multifunctional system has potential applications in bone tissue engineering and dental fields.

JOURNAL OF MATERIALS RESEARCH (2022)

Add to Collection

Article Engineering, Biomedical

A 3D Osteosarcoma Model with Bone-Mimicking Cues Reveals a Critical Role of Bone Mineral and Informs Drug Discovery

Eva C. Gonzalez Diaz et al.

Summary: In this study, a microribbon-based osteosarcoma (OS) model with bone-mimicking compositions was developed to investigate OS signaling and drug response. The role of hydroxyapatite in 3D culture in supporting OS signaling and drug resistance was elucidated. The model was validated using established OS cell lines, patient-derived xenograft (PDX) cell lines, and animal models. Integration of the 3D OS PDX models with RNA-sequencing identified druggable targets and predicted drug response. The microribbon-based 3D OS models are a novel experimental tool for studying OS heterogeneity and drug resistance mechanisms.

ADVANCED HEALTHCARE MATERIALS (2022)

Add to Collection

Article Engineering, Biomedical

Amorphous Precursor-Mediated Calcium Phosphate Coatings with Tunable Microstructures for Customized Bone Implants

Li-Na Wang et al.

Summary: Inspired by natural biomineral formation, this study fabricated CaP coatings with tunable microstructures mediated by an amorphous metastable phase, precisely controlled by polyaspartic acid and Mg2+. The significant differences in cell biological behaviors and osseointegration in different types of rats and bones under varying CaP coatings were demonstrated.

ADVANCED HEALTHCARE MATERIALS (2022)

Add to Collection

Article Engineering, Biomedical

Spatiotemporal Delivery of pBMP2 and pVEGF by a Core-Sheath Structured Fiber-Hydrogel Gene-Activated Matrix Loaded with Peptide-Modified Nanoparticles for Critical-Sized Bone Defect Repair

Shan He et al.

Summary: A gene-activated biomimetic composite scaffold has been developed for the treatment of large segmental bone defects. This scaffold allows spatiotemporal release of genes to promote osteogenic differentiation of preosteoblasts in vitro and accelerate bone healing in vivo through angiogenesis and osteogenesis.

ADVANCED HEALTHCARE MATERIALS (2022)

Add to Collection

Article Engineering, Biomedical

PoreScript: Semi-automated pore size algorithm for scaffold characterization

Dana Jenkins et al.

Summary: The pore size of a scaffold has significant effects on various physical properties in tissue engineering. Manual measurements using ImageJ/FIJI are time-consuming and subjective. In this study, a new MATLAB algorithm called PoreScript was developed and validated using different scaffold fabrication methods. The results demonstrate the accuracy and versatility of PoreScript.

BIOACTIVE MATERIALS (2022)

Add to Collection

Article Materials Science, Multidisciplinary

3D printed hydroxyapatite-Zn2+functionalized starch composite bone grafts for orthopedic and dental applications

Arjak Bhattacharjee et al.

Summary: This study demonstrates the feasibility of fabricating hydroxyapatite-Zn2+ functionalized starch composites as artificial bone graft substitutes using a 3D printer. The mechanical strength of the grafts is significantly improved through parametric optimization and functionalization, and the functionalized grafts also exhibit high antibacterial efficacy.

MATERIALS & DESIGN (2022)

Add to Collection

Article Multidisciplinary Sciences

Interleukin-1 contributes to clonal expansion and progression of bone marrow fibrosis in JAK2V617F-induced myeloproliferative neoplasm

Mohammed Ferdous-Ur Rahman et al.

Summary: Chronic inflammation is closely related to myeloproliferative neoplasms (MPN). IL-1 signaling plays a pathogenic role in MPN disease progression, and targeting of IL-1R1 could be an effective strategy for the treatment of myelofibrosis.

NATURE COMMUNICATIONS (2022)

Add to Collection

Article Engineering, Multidisciplinary

High-strength calcium silicate-incorporated magnesium phosphate bone cement with osteogenic potential for orthopedic application

Wenjuan Liu et al.

Summary: This study developed a composite bone cement with high compressive strength and desirable bioactivity by incorporating calcium silicate bioceramic into magnesium phosphate bone cement. The composite bone cement showed significantly higher compressive strength compared to traditional bone cements and demonstrated apatite mineralization ability and moderate degradation behavior.

COMPOSITES PART B-ENGINEERING (2022)

Add to Collection

Review Cell & Tissue Engineering

Can intracellular Staphylococcus aureus in osteomyelitis be treated using current antibiotics? A systematic review and narrative synthesis

Anja R. Zelmer et al.

Summary: Staphylococcus aureus, the predominant pathogen in osteomyelitis, can persist by forming intracellular reservoirs and adapting as small-colony variants (SCVs), reducing susceptibility to antibiotics. However, there are no evidence-based clinical guidelines for treating intracellular S. aureus infections in osteomyelitis. A systematic review of the literature found inconclusive results due to various methodologies employed. More standardized research is needed to improve understanding and treatment outcomes.

BONE RESEARCH (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Additive Manufacturing of Material Scaffolds for Bone Regeneration: Toward Application in the Clinics

Charlotte Garot et al.

Summary: This paper reviews the state-of-the-art materials and AM techniques used in the fabrication of 3D-printed bone scaffolds in bone tissue engineering. The advantages and drawbacks of these materials and techniques are highlighted, with specific criteria for material selection identified. Different combinations of materials and AM techniques are found to be most relevant for specific clinical applications.

ADVANCED FUNCTIONAL MATERIALS (2021)

Add to Collection

Review Chemistry, Multidisciplinary

Tailored Mesoporous Inorganic Biomaterials: Assembly, Functionalization, and Drug Delivery Engineering

Yidong Zou et al.

Summary: Mesoporous biomaterials as nanocarriers show great potential in drug-targeted therapy, becoming a hot topic in interdisciplinary research. Understanding assembly mechanisms, functionalization methods, and the impact of physicochemical parameters on DDS application will contribute to significant advancements in disease therapeutics.

ADVANCED MATERIALS (2021)

Add to Collection

Article Engineering, Biomedical

Development of systemic immune dysregulation in a rat trauma model of biomaterial-associated infection

Casey E. Vantucci et al.

Summary: Orthopedic biomaterial-associated infections can lead to systemic and local immune dysregulation, with infected groups lacking a regulated and coordinated systemic cytokine response compared to non-infected controls. High levels of MDSCs were most correlated with the infection group, while high levels of T cells were most correlated with the control group.

BIOMATERIALS (2021)

Add to Collection

Article Engineering, Environmental

A self-healing coating containing curcumin for osteoimmunomodulation to ameliorate osseointegration

Bo Li et al.

Summary: Novel coatings with self-healing and osteoimmunomodulation functions were fabricated to enhance corrosion resistance and osseointegration of Mg-based endosseous implants. The coatings showed effective protection to Mg in vitro and in vivo through cFMSNs as corrosion inhibitors, while curcumin release improved immune microenvironment favoring osteo-differentiation and extracellular matrix mineralization of bone marrow stem cells, leading to better osseointegration. Coatings with higher cFMSNs content exhibited superior immunomodulatory efficiency and achieved the best osseointegration in vivo.

CHEMICAL ENGINEERING JOURNAL (2021)

Add to Collection

Review Engineering, Biomedical

Natural medicine delivery from biomedical devices to treat bone disorders: A review

Susmita Bose et al.

Summary: With an aging population and increasing life expectancy, orthopedic defects and bone graft surgeries are on the rise globally. The integration of natural medicinal compounds into bone scaffolds shows promising potential in guiding bone regeneration and healing processes.

ACTA BIOMATERIALIA (2021)

Add to Collection

Review Pharmacology & Pharmacy

Overcoming barriers by local drug delivery with liposomes

S. G. Antimisiaris et al.

Summary: Localized or topical drug administration, in combination with nanoparticulate formulations like liposomes, can offer advantages such as prolonged retention of high drug loads, controlled release, reduced side effects, and increased protection from harsh environments. Targeted liposomal formulations may enhance these therapeutic advantages in drug delivery.

ADVANCED DRUG DELIVERY REVIEWS (2021)

Add to Collection

Review Biochemistry & Molecular Biology

Metal-Curcumin Complexes in Therapeutics: An Approach to Enhance Pharmacological Effects of Curcumin

Sahdeo Prasad et al.

Summary: Curcumin, an active compound in turmeric, has various pharmacological properties, but its effectiveness is limited by its nature. Metal-curcumin complexes have been developed to enhance solubility and absorption, showing positive effects against chronic diseases.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Add to Collection

Article Materials Science, Biomaterials

Evaluation of the in vivo behavior of antibacterial gold nanoparticles for potential biomedical applications

Le Wang et al.

Summary: Pharmacokinetics plays a critical role in the clinical applicability of nanomaterials. By studying the pharmacokinetics of A/M-Au NPs, it was found that they exhibit appropriate pharmacokinetic profile and high biosafety, paving the way for their potential biomedical applications.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

Add to Collection

Article Nanoscience & Nanotechnology

Controlled Delivery of Curcumin and Vitamin K2 from Hydroxyapatite-Coated Titanium Implant for Enhanced in Vitro Chemoprevention, Osteogenesis, and in Vivo Osseointegration

Naboneeta Sarkar et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

Add to Collection

Editorial Material Oncology

Cabozantinib: a new perspective for advanced bone sarcoma

Franca Fagioli et al.

LANCET ONCOLOGY (2020)

Add to Collection

Article Materials Science, Biomaterials

Cytotoxic and osteogenic effects of crocin and bicarbonate from calcium phosphates for potential chemopreventative and anti-inflammatory applications in vitro and in vivo

Caitlin Koski et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

Add to Collection

Article Nutrition & Dietetics

Antimicrobial Properties of Magnesium Open Opportunities to Develop Healthier Food

Keren Demishtein et al.

NUTRIENTS (2019)

Add to Collection

Article Multidisciplinary Sciences

Double-slit photoelectron interference in strong-field ionization of the neon dimer

Maksim Kunitski et al.

NATURE COMMUNICATIONS (2019)

Add to Collection

Article Nanoscience & Nanotechnology

Bacterial Inhibition and Osteoblast Adhesion on Ti Alloy Surfaces Modified by Poly(PEGMA-r-Phosmer) Coating

Xinnan Cui et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

Add to Collection

Article Multidisciplinary Sciences

Ancient drug curcumin impedes 26S proteasome activity by direct inhibition of dual-specificity tyrosine-regulated kinase 2

Sourav Banerjee et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Add to Collection

Article Chemistry, Multidisciplinary

Trace fluorine substituted calcium deficient hydroxyapatite with excellent osteoblastic activity and antibacterial ability

Liping Wang et al.

CRYSTENGCOMM (2018)

Add to Collection

Article Materials Science, Ceramics

Learning from Nature: Using bioinspired approaches and natural materials to make porous bioceramics

Francesco Baino et al.

INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY (2017)

Add to Collection

Article Materials Science, Biomaterials

Influences of doping mesoporous magnesium silicate on water absorption, drug release, degradability, apatite-mineralization and primary cells responses to calcium sulfate based bone cements

Zhengrong Gu et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2017)

Add to Collection

Letter Biochemistry & Molecular Biology

t Vincristine alleviates adriamycin-induced nephropathy through stabilizing actin cytoskeleton

Lei Yin et al.

CELL AND BIOSCIENCE (2017)

Add to Collection

Review Engineering, Biomedical

Bone grafts and biomaterials substitutes for bone defect repair: A review

Wenhao Wang et al.

BIOACTIVE MATERIALS (2017)

Add to Collection

Article Chemistry, Multidisciplinary

Surface-Adaptive Gold Nanoparticles with Effective Adherence and Enhanced Photothermal Ablation of Methicillin-Resistant Staphylococcus aureus Biofilm

Dengfeng Hu et al.

ACS NANO (2017)

Add to Collection

Article Materials Science, Biomaterials

3D-printed bioceramic scaffolds with a Fe3O4/graphene oxide nanocomposite interface for hyperthermia therapy of bone tumor cells

Yongliang Zhang et al.

JOURNAL OF MATERIALS CHEMISTRY B (2016)

Add to Collection

Review Cell Biology

Roles of NF-κB in Cancer and Inflammatory Diseases and Their Therapeutic Approaches

Mi Hee Park et al.

CELLS (2016)

Add to Collection

Review Pharmacology & Pharmacy

Biomaterial strategies for engineering implants for enhanced osseointegration and bone repair

Rachit Agarwal et al.

ADVANCED DRUG DELIVERY REVIEWS (2015)

Add to Collection

Article Materials Science, Biomaterials

Surface modification of titanium with curcumin: a promising strategy to combat fibrous encapsulation

Ronghan He et al.

JOURNAL OF MATERIALS CHEMISTRY B (2015)

Add to Collection

Article Nanoscience & Nanotechnology

Polycaprolactone-Coated 3D Printed Tricalcium Phosphate Scaffolds for Bone Tissue Engineering: In Vitro Alendronate Release Behavior and Local Delivery Effect on In Vivo Osteogenesis

Solaiman Tarafder et al.

ACS APPLIED MATERIALS & INTERFACES (2014)

Add to Collection

Review Oncology

Translational biology of osteosarcoma

Maya Kansara et al.

NATURE REVIEWS CANCER (2014)

Add to Collection

Article Engineering, Biomedical

A new metaphyseal bone defect model in osteoporotic rats to study biomaterials for the enhancement of bone healing in osteoporotic fractures

Volker Alt et al.

ACTA BIOMATERIALIA (2013)

Add to Collection

Article Engineering, Biomedical

The effect of ligand composition on the in vivo fate of multidentate poly(ethylene glycol) modified gold nanoparticles

Xiangsheng Liu et al.

BIOMATERIALS (2013)

Add to Collection

Article Engineering, Biomedical

In vivo stimulation of bone formation by aluminum and oxygen plasma surface-modified magnesium implants

Hoi Man Wong et al.

BIOMATERIALS (2013)

Add to Collection

Article Engineering, Biomedical

Bone formation induced by strontium modified calcium phosphate cement in critical-size metaphyseal fracture defects in ovariectomized rats

Ulrich Thormann et al.

BIOMATERIALS (2013)

Add to Collection

Article Cell & Tissue Engineering

Microwave-sintered 3D printed tricalcium phosphate scaffolds for bone tissue engineering

Solaiman Tarafder et al.

JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2013)

Add to Collection

Article Materials Science, Multidisciplinary

Bone tissue engineering using 3D printing

Susmita Bose et al.

MATERIALS TODAY (2013)

Add to Collection

Article Materials Science, Biomaterials

3D printed tricalcium phosphate bone tissue engineering scaffolds: effect of SrO and MgO doping on in vivo osteogenesis in a rat distal femoral defect model

Solaiman Tarafder et al.

BIOMATERIALS SCIENCE (2013)

Add to Collection

Review Engineering, Biomedical

Calcium phosphate ceramic systems in growth factor and drug delivery for bone tissue engineering: A review

Susmita Bose et al.

ACTA BIOMATERIALIA (2012)

Add to Collection

Article Chemistry, Medicinal

Curcumin increases rat mesenchymal stem cell osteoblast differentiation but inhibits adipocyte differentiation

Qiaoli Gu et al.

PHARMACOGNOSY MAGAZINE (2012)

Add to Collection

Review Cell Biology

Biomaterial-Associated Infection: Locating the Finish Line in the Race for the Surface

Henk J. Busscher et al.

SCIENCE TRANSLATIONAL MEDICINE (2012)

Add to Collection

Article Engineering, Biomedical

Cytotoxicity of silica nanoparticles through exocytosis of von Willebrand factor and necrotic cell death in primary human endothelial cells

Alexander T. Bauer et al.

BIOMATERIALS (2011)

Add to Collection

Article Engineering, Biomedical

The in vitro stability and in vivo pharmacokinetics of curcumin prepared as an aqueous nanoparticulate formulation

Chandana Mohanty et al.

BIOMATERIALS (2010)

Add to Collection

Article Engineering, Biomedical

Multiscale osteointegration as a new paradigm for the design of calcium phosphate scaffolds for bone regeneration

Sheeny K. Lan Levengood et al.

BIOMATERIALS (2010)

Add to Collection

Article Engineering, Biomedical

Coating of biomaterial scaffolds with the collagen-mimetic peptide GFOGER for bone defect repair

Abigail M. Wojtowicz et al.

BIOMATERIALS (2010)

Add to Collection

Article Materials Science, Ceramics

3D printing of bone substitute implants using calcium phosphate and bioactive glasses

Christian Bergmann et al.

JOURNAL OF THE EUROPEAN CERAMIC SOCIETY (2010)

Add to Collection

Article Engineering, Biomedical

Dynamic processes involved in the pre-vascularization of silk fibroin constructs for bone regeneration using outgrowth endothelial cells

Sabine Fuchs et al.

BIOMATERIALS (2009)

Add to Collection

Article Engineering, Biomedical

In vitro and in vivo evaluation of the surface bioactivity of a calcium phosphate coated magnesium alloy

Liping Xu et al.

BIOMATERIALS (2009)

Add to Collection

Article Oncology

L-Glutamine Use in the Treatment and Prevention of Mucositis and Cachexia: A Naturopathic Perspective

Jody E. Noe

INTEGRATIVE CANCER THERAPIES (2009)

Add to Collection

Article Engineering, Biomedical

Alendronate-hydroxyapatite nanocomposites and their interaction with osteoclasts and osteoblast-like cells

Elisa Boanini et al.

BIOMATERIALS (2008)

Add to Collection

Article Agriculture, Multidisciplinary

Curcumin, a known phenolic from curcuma longa, attenuates the virulence of Pseudomonas aeruginosa PAO1 in whole plant and animal pathogenicity models

Thimmarax Rudrappa et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2008)

Add to Collection

Article Biochemistry & Molecular Biology

Biomimetic growth of hydroxyapatite on gelatin films doped with sodium polyacrylate

A Bigi et al.

BIOMACROMOLECULES (2000)

Add to Collection

© Peeref 2019-2024. All rights reserved.