4.1 Article

An Unusual Case of Catastrophic Antiphospholipid Syndrome in an Elderly Man

Journal

CUREUS JOURNAL OF MEDICAL SCIENCE
Volume 15, Issue 2, Pages -

Publisher

CUREUS INC
DOI: 10.7759/cureus.34810

Keywords

catastrophic apls; apls; aps; antiphospholipid syndrome; catastrophic aps; catastrophic antiphospholipid antibody syndrome(caps); caps

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Antiphospholipid syndrome (APS) is a condition where the body produces antibodies that lead to the formation of arterial and venous blood clots. Catastrophic antiphospholipid syndrome (CAPS) is a rare subtype characterized by acute thrombotic microangiography. CAPS is triggered by various conditions or factors such as genetics, infection, surgery, medications, and malignancy. This report presents a unique case of CAPS in a 63-year-old male patient.
Antiphospholipid syndrome (APS) is a condition in which the body produces antiphospholipid antibodies, resulting in arterial and venous thrombosis. Catastrophic antiphospholipid syndrome (CAPS) is a rare APS subtype characterized by acute thrombotic microangiography. Antiphospholipid antibodies cause thrombosis through activating and inhibiting properties. CAPS is caused by conditions or factors that trigger the production of antiphospholipid antibodies: genetics that increases the risk of antiphospholipid antibody-associated thrombosis, infection, surgery, medications, and malignancy. We present a unique case of CAPS in a 63-year-old male patient.

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