4.1 Review

Korean Brain Tumor Society Consensus Review for the Practical Recommendations on Glioma Management in Korea

Journal

JOURNAL OF KOREAN NEUROSURGICAL SOCIETY
Volume 66, Issue 3, Pages 308-+

Publisher

KOREAN NEUROSURGICAL SOC
DOI: 10.3340/jkns.2023.0046

Keywords

Glioma; Korean Brain Tumor Society; Off-label drug use; Consensus

Ask authors/readers for more resources

Recent updates in genomic-integrated glioma classification have caused confusion in clinical practice, but the Korean Brain Tumor Society conducted a questionnaire survey to gain consensus on risk group categorization and treatment preferences. They found agreement on dichotomic definition of risk groups and consistent decisions based on WHO grade and risk group for treatment protocols. Temporary consensus and available options will aid management until more evidence is accumulated under the new classification system.
Recent updates in genomic-integrated glioma classification have caused confusion in current clinical practice, as management protocols and health insurance systems are based on evidence from previous diagnostic classifications. The Korean Brain Tumor Society conducted an electronic questionnaire for society members, asking for their ideas on risk group categorization and preferred treatment for each individual diagnosis listed in the new World Health Organization (WHO) classification of gliomas. Additionally, the current off-label drug use (OLDU) protocols for glioma management approved by the Health Insurance Review and Assessment Service (HIRA) in Korea were investigated. A total of 24 responses were collected from 20 major institutes in Korea. A consensus was reached on the dichotomic definition of risk groups for glioma prognosis, using age, performance status, and extent of resection. In selecting management protocols, there was general consistency in decisions according to the WHO grade and the risk group, regardless of the individual diagnosis. As of December 2022, there were 22 OLDU protocols available for the management of gliomas in Korea. The consensus and available options described in this report will be temporarily helpful until there is an accumulation of evidence for effective management under the new classification system for gliomas.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.1
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available