An experimental study on effects of interventional stent treatment on hemodynamics in elastic aneurysms

Cerebral hemodynamics plays a significant role in the growth and rupture of intracranial aneurysms (IAs), which pose a threat to human health. Real time visualization experiment is applied to observe fluid flow in the aneurysm using a high-speed camera in this paper with a focus on the influences of interventional stent treatment for elastic aneurysms on hemodynamics. The effects of blood flow rate, wall compliance as well as stent on IA hemodynamics patterns and flow field are explored. It indicated that, compared to the low inflow rate ranging between 12 and 18 l/h, there are less steady flow field variables and poorer stability in the aneurysm compared to that at high inflow rate ranging between 11.5 and 22 l/h. Wall compliance, allowing blood to pass in and out aneurysm more easily, acts as a buffer, especially at an excessive inflow range. In addition, the stent not only attenuates the effect of wall compliance but also acts as a flow diverter in the blood vessel to the reduction in the risk of aneurysm rupture. Consequently, this paper offers a contribution to clinical reference in predicting the risk of IA rupture and holds great promise for optimal treatment.

Automated summary

This paper examines the effects of interventional stent treatment on the cerebral hemodynamics of elastic aneurysms. It finds that higher blood flow rates and greater wall compliance provide a more stable flow environment, while the stent attenuates the impact of wall compliance and acts as a flow diverter to reduce the risk of aneurysm rupture.