Enzyme-immobilized spherical covalent organic frameworks as nanoreactors for heterogeneous biocatalysis

Uniform spherical covalent organic frameworks (COFs) were prepared at room temperature, which could immobilize horseradish peroxidase (HRP) with high loading capacity. The HRP@COF exhibited good reusability and enhanced tolerance to extreme circumstances.

Automated summary

Uniform spherical covalent organic frameworks (COFs) were synthesized at room temperature and used to immobilize horseradish peroxidase (HRP) with high loading capacity. The resulting HRP@COF displayed excellent reusability and enhanced tolerance to extreme conditions.