4.1 Article

Neuromyelitis Optica: A Case Report From a Radiological Perspective

Journal

CUREUS JOURNAL OF MEDICAL SCIENCE
Volume 15, Issue 5, Pages -

Publisher

SPRINGERNATURE
DOI: 10.7759/cureus.38945

Keywords

transverse myelitis; aquaporins-4; magnetic resonance imaging ( mri); azathioprine; devic's neuromyelitis optica

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Neuromyelitis optica (NMO) is a central nervous system disorder characterized by optic neuritis and myelitis. MRI and serological examination are crucial for diagnosis, and treatment primarily involves the use of steroids. However, there may be unique cases that deviate from the typical presentation.
Neuromyelitis optica (NMO), also known as Devic's disease, is a chronic inflammatory disorder of the optic nerve and the spinal cord. Similar to multiple sclerosis, it has a relapsing and remitting characteristic. The disease is characterized by optic neuritis and longitudinal extensive inflammation of the spinal cord. Magnetic resonance imaging (MRI) is the modality of choice for this disorder. The serological examination also shows the presence of aquaporin-4 (AQP4) autoantibodies. MRI shows longitudinal extensive transverse myelitis and signs of optic neuritis such as inflammation of the optic nerve. The treatment is based on intravenous corticosteroids with or without plasmapheresis. The current case is a 25-year-old African American male patient who presented with multiple sclerosis-like symptoms (i.e., optic neuritis and transverse myelitis) but turned out to have NMO. Serological examination reveals the absence of AQP4 autoantibodies. A radiological examination showed swelling in the cervical cord. This case report strongly focuses on the radiological findings of NMO.

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