Incidentally Discovered Mucosal Prolapse of the Colon During Colorectal Cancer Screening: A Case Report

Colonic mucosal prolapse syndrome is a rare type of non-neoplastic non-inflammatory colorectal polyps that can mimic neoplastic lesions. We present a case of a 65-year-old man with mucosal prolapse syndrome, incidentally, discovered during colorectal cancer screening. The patient was asymptomatic, and his physical exam and laboratory test results were unremarkable. During a colonoscopy, the physician removed three small tubular adenomas and two pedunculated polyps suspicious of neoplasms. Retroflexion revealed small internal hemorrhoids. The histology of the larger polyps revealed mucosal prolapse features, while the smaller polyps displayed features consistent with tubular adenomas. Management involves the removal of associated polyps during colonoscopy, followed by surveillance colonoscopy to detect any recurrent polyps or early signs of colorectal cancer. Accurate diagnosis is crucial to avoid unnecessary interventions and ensure appropriate management.

Automated summary

Colonic mucosal prolapse syndrome is a rare condition that resembles neoplastic lesions and was incidentally found during colorectal cancer screening in a 65-year-old man. The patient was asymptomatic and had normal physical exam and laboratory test results. Colonoscopy revealed the presence of tubular adenomas and pedunculated polyps suspicious of neoplasms, along with small internal hemorrhoids. Histology confirmed the diagnosis of mucosal prolapse syndrome in the larger polyps, while the smaller polyps were consistent with tubular adenomas. Management involves removing associated polyps and conducting surveillance colonoscopy for monitoring recurrence and early signs of colorectal cancer.