Journal
JOURNAL OF MATERIALS CHEMISTRY B
Volume 11, Issue 27, Pages 6225-6248Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d3tb00905j
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The composition, morphology, and mechanical performance of nanomaterials are crucial for tissue engineering. Tubular nanomaterials (TNs), including carbon nanotubes, titanium oxide nanotubes, halloysite nanotubes, silica nanotubes, and hydroxyapatite nanotubes, have shown great potential in various applications due to their high surface area, versatile surface chemistry, well-defined mechanical properties, excellent biocompatibility, and monodispersity. This review focuses on the recent developments in TN-based biomaterials for structural tissue engineering, with a strong emphasis on bone tissue regeneration. It includes a detailed literature review on TN-based orthopedic coatings for metallic implants and composite scaffolds to enhance in vivo bone regeneration.
Nanomaterial composition, morphology, and mechanical performance are critical parameters for tissue engineering. Within this rapidly expanding space, tubular nanomaterials (TNs), including carbon nanotubes (CNTs), titanium oxide nanotubes (TNTs), halloysite nanotubes (HNTs), silica nanotubes (SiNTs), and hydroxyapatite nanotubes (HANTs) have shown significant potential across a broad range of applications due to their high surface area, versatile surface chemistry, well-defined mechanical properties, excellent biocompatibility, and monodispersity. These include drug delivery vectors, imaging contrast agents, and scaffolds for bone tissue engineering. This review is centered on the recent developments in TN-based biomaterials for structural tissue engineering, with a strong focus on bone tissue regeneration. It includes a detailed literature review on TN-based orthopedic coatings for metallic implants and composite scaffolds to enhance in vivo bone regeneration.
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