Ultrafiltration for bovine serum albumin protein by all alumina porous membranes

In this study, three types of Al2O3 powders were used as raw materials to fabricate and evaluate the performance of all-alumina multi-layer filters, and an attempt was made to fabricate an ultrafiltration filter that separates and removes proteins. When bovine serum albumin (BSA, molecular weight 66,000) was used as the protein, a very high rejection rate of 91.9 % was obtained even under mild conditions with a differential pressure of 1 atm or less.& COPY;2023 The Ceramic Society of Japan. All rights reserved.

Automated summary

In this study, the performance of all-alumina multi-layer filters was evaluated by using three types of Al2O3 powders as raw materials, and an attempt was made to fabricate an ultrafiltration filter that can separate and remove proteins. When bovine serum albumin (BSA, molecular weight 66,000) was used as the protein, a very high rejection rate of 91.9% was achieved even under mild conditions with a differential pressure of 1 atm or less.