Long Noncoding RNAs in Ovarian Cancer-Functions and Clinical Applications

Long noncoding RNAs (lncRNAs) are RNA molecules with a length of more than 200 nt that have been discovered in recent years. LncRNAs can participate in regulating gene expression and various biological activities through multiple pathways, such as at the epi-genetic level, transcriptional level, and posttranscriptional level. In recent years, with the increasing understanding of lncRNAs, a large number of studies have shown that lncRNAs are closely related to ovarian cancer and participate in its occurrence and development, providing a new method to investigate ovarian cancer. In this review, we analyzed and summarized the relationship between various lncRNAs and ovarian cancer in terms of occurrence, development, and clinical significance, in order to provide a theoretical basis for basic research and clinical application of ovarian cancer.

Automated summary

Long noncoding RNAs (lncRNAs) are RNA molecules with a length of more than 200 nt that can regulate gene expression and biological activities in ovarian cancer through various pathways. This review analyzes the relationship between lncRNAs and ovarian cancer in terms of occurrence, development, and clinical significance, providing a theoretical basis for further research and clinical applications.