Green nanoparticle synthesis at scale: a perspective on overcoming the limits of pulsed laser ablation in liquids for high-throughput production

Nanoparticles have become increasingly important for a variety of applications, including medical diagnosis and treatment, energy harvesting and storage, catalysis, and additive manufacturing. The development of nanoparticles with different compositions, sizes, and surface properties is essential to optimize their performance for specific applications. Pulsed laser ablation in liquid is a green chemistry approach that allows for the production of ligand-free nanoparticles with diverse shapes and phases. Despite these numerous advantages, the current production rate of this method remains limited, with typical rates in the milligram per hour range. To unlock the full potential of this technique for various applications, researchers have dedicated efforts to scaling up production rates to the gram-per-hour range. Achieving this goal necessitates a thorough understanding of the factors that limit pulsed laser ablation in liquid (PLAL) productivity, including laser, target, liquid, chamber, and scanner parameters. This perspective article explores these factors and provides a roadmap for increasing PLAL productivity that can be adapted to specific applications. By carefully controlling these parameters and developing new strategies for scaling up production, researchers can unlock the full potential of pulsed laser ablation in liquids.

Automated summary

Nanoparticles are increasingly important for various applications, and pulsed laser ablation in liquid is a promising method for their production. However, the current production rate is limited, and efforts are being made to scale up the production rate to unlock its full potential. Controlling parameters and developing new strategies can increase the productivity of pulsed laser ablation in liquids.