Journal
ADVANCES IN NUTRITION
Volume 7, Issue 3, Pages 544-555Publisher
ELSEVIER SCIENCE INC
DOI: 10.3945/an.115.011189
Keywords
calcium; phosphorus; bone health; cardiovascular diseases; vitamin D
Categories
Funding
- American Society for Nutrition (ASN)
- National Dairy Council
- Dairy Australia
- Pharmavite
- Kraft Foods
- Dairy Research Institute
- Nestle
- NIH [HL-069229, HL-114806]
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Bone and heart health are linked through a variety of cellular, endocrine, and metabolic mechanisms, including the bidirectional effects of mineral-regulating hormones parathyroid hormone and fibroblast growth factor 23. Nutrition plays an important role in the development of both cardiovascular and bone disease. This review describes current knowledge on the relations between the cardiovascular system and bone and the influence of key nutrients involved in mineral metabolism-calcium, vitamin D, and phosphorus-on heart and bone health, as well as the racial/ethnic differences in cardiovascular disease and osteoporosis and the influence that nutrition has on these disparities.
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