First characterization of the intestinal microbiota in healthy Tunisian adults using 16S rRNA gene sequencing

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Two Blautia Species Associated with Visceral Fat Accumulation: A One-Year Longitudinal Study

Naoki Ozato et al.

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Reproducible and opposing gut microbiome signatures distinguish autoimmune diseases and cancers: a systematic review and meta-analysis

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MICROBIOME (2022)

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Gut Microbiota Characteristics of People with Obesity by Meta-Analysis of Existing Datasets

Jinhua Gong et al.

Summary: This study identified microbial markers associated with obesity through an integrated analysis of a large number of fecal samples. The results showed significant differences in bacterial communities between obese and control groups, and certain bacteria and metabolic pathways were associated with obesity. These findings provide important insights for the management of obesity.

NUTRIENTS (2022)

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Association between the Blautia/Bacteroides Ratio and Altered Body Mass Index after Bariatric Surgery

Yoonhong Kim et al.

Summary: This study investigates the changes in gut microbiota before and after bariatric surgery and evaluates the association between gut microbial shift and altered body mass index (BMI). The results show that patients who underwent bariatric surgery had increased alpha-diversity, decreased Blautia, and increased Bacteriodes, and the Blautia/Bacteroides ratio was positively correlated with BMI.

ENDOCRINOLOGY AND METABOLISM (2022)

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Muhammad Afzaal et al.

Summary: The human gut contains a complex microbial community, which forms a connecting axis with other organs and plays a vital role in host-microbe interactions. Dysbiosis of the gut microbiota is linked to various human diseases. Understanding the role of gut microbiota in health and disease is crucial for maintaining health and treating diseases.

FRONTIERS IN MICROBIOLOGY (2022)

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Article Biochemistry & Molecular Biology

Diet-gut microbiota interactions on cardiovascular disease

Xufei Zhang et al.

Summary: Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality worldwide. The gut microbiota plays a vital role in CVD development and can be influenced by dietary nutrients. The crosstalk between diet and microbiota regulates CVD progression through various mechanisms, including endotoxemia, inflammation, gut barrier dysfunction, and lipid metabolism dysfunction. Microbial metabolites such as trimethylamine-N-oxide (TMAO), secondary bile acids (BAs), short chain fatty acids (SCFAs), and aromatic amino acids (AAAs) contribute to CVD pathogenesis. Dietary interventions targeting the gut microbiota may serve as novel strategies for CVD management.

COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2022)

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Kaijian Hou et al.

Summary: The role of microbiota in health and disease is significant, contributing to homeostasis and immune regulation. Dysbiosis of microbiota can lead to disease progression, associated with dysregulation of community composition, modulation of host immune response, and induction of chronic inflammation. Clinical approaches utilizing microbiota, such as microbiota modulation and fecal microbial transplantation, can be effective for disease treatment.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2022)

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PEERJ (2021)

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Alexander Koliada et al.

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BMC MICROBIOLOGY (2021)

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MAYO CLINIC PROCEEDINGS (2021)

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Characteristics of gut microbiota in people with obesity

Mengmeng Duan et al.

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First characterization of the intestinal microbiota in healthy Tunisian adults using 16S rRNA gene sequencing

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