Long-Term SARS-CoV-2 Antibody Seroprevalence in Blood Donors, Italy

We evaluated SARS-CoV-2 antibody response in volun- tary blood donors in Italy at different timepoints. Immedi- ately after lockdown easing, 908/25,657 donors (3.5%) had low IgG titers against nucleocapsid. In the next 2 years, titers increased despite few COVID-19 symptoms. On multivariate analysis, allergic rhinitis was associated with reduced risk for symptomatic COVID-19.

Automated summary

We investigated the SARS-CoV-2 antibody response in voluntary blood donors in Italy at different timepoints. Immediately after lockdown easing, 908 out of 25,657 donors (3.5%) had low IgG titers against nucleocapsid. In the following two years, titers increased despite few COVID-19 symptoms. Allergic rhinitis was found to be associated with a reduced risk for symptomatic COVID-19 according to multivariate analysis.