4.5 Article

Bilateral Stereotactic Thalamotomy for Bilateral Musician's Hand Dystonia

Journal

WORLD NEUROSURGERY
Volume 92, Issue -, Pages -

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.wneu.2016.05.017

Keywords

Focal hand dystonia; Musician's dystonia; Thalamotomy

Funding

  1. Health Labor Sciences Research Grant in Japan [0016151]
  2. Ministry of Education, Culture, Sports, Science, and Technology in Japan [23592144]
  3. St. Jude Medical Japan Co., Ltd
  4. Daiichi-Sankyo Japan Co., Ltd.
  5. Grants-in-Aid for Scientific Research [23592144] Funding Source: KAKEN

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BACKGROUND: Focal hand dystonia in musicians, also known as musician's dystonia, is a task-specific movement disorder characterized by unwanted involuntary muscle contractions occurring only when playing a musical instrument. CASE DESCRIPTION: Case 1 was a 50-year-old female professional pianist who underwent staged bilateral ventro-oral (Vo) thalamotomy, with an interval between the first and second surgery of 4 years. The first surgery (right Vo thalamotomy) led to significant improvements in dystonic symptoms without any complications. Pre- and postoperative Tubiana's musician's dystonia scale (TMDS) scores were 2 and 5, respectively. The second surgery (left Vo thalamotomy) also led to significant improvements in dystonic symptoms, with dysarthria and verbal recall disturbance resolving within 3 months. Pre-and postoperative TMDS scores were 2 and 5, respectively. The patient was subsequently able to return to live-stage performances. Case 2 was a 48-year-old male clarinet repair technician who underwent staged bilateral Vo thalamotomy, with an interval between the first and second surgery of 13 months. The first surgery (right Vo thalamotomy) led to dramatic improvements in symptoms without any complications. Pre-and postoperative TMDS scores were 2 and 5, respectively. The second surgery (left Vo thalamotomy) also led to significant improvements in symptoms with transient hypophonia. Pre- and postoperative TMDS scores were 2 and 5, respectively. The patient was subsequently able to return to work without difficulty. CONCLUSIONS: The findings in these 2 cases indicate the utility of bilateral stereotactic Vo thalamotomy in the treatment of medically intractable musician's dystonia affecting both hands.

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