4.5 Review

Bacterial peptide transporters: Messengers of nutrition to virulence

Journal

VIRULENCE
Volume 8, Issue 3, Pages 297-309

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/21505594.2016.1221025

Keywords

ABC transporters; antimicrobial therapy; bacterial pathogens; metabolism; peptide transporters; PTR transporters; virulence

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Bacteria possess numerous peptide transporters for importing peptides as nutrients. However, these peptide transporters are now consistently reported to play a role in the virulence of various bacterial pathogens. Their ability to transport peptides has implications in antibacterial therapy as well. Therefore, it would be instrumental to have complete knowledge about the role of peptide transporters in mediating this cross connection between metabolism and pathogenesis. Studies on various peptide transporters in bacterial pathogens have improved our understanding of this field. In this review, we have given an overview of the functioning of bacterial peptide transporters and their contribution in virulence of major bacterial pathogens.

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