4.7 Article

Label-free electrochemical immunosensor for detection of insulin-like growth factor-1 (IGF-1) using a specific monoclonal receptor on electrospun Zein-based nanofibers/rGO-modified electrode

Related references

Note: Only part of the references are listed.
Article Chemistry, Analytical

Self-assembled monolayer-assisted label-free electrochemical genosensor for specific point-of-care determination of Haemophilus influenzae

Hessamaddin Sohrabi et al.

Summary: This research demonstrates a label-free electrochemical-based genosensing assay for the sensitive detection of the L-fuculokinase genome related to Haemophilus influenzae (H. influenzae). Multiple electrochemical modifier-tagged agents were effectively used to enhance the electrochemical responses. The designed genosensing bio-platform achieved low detection and quantification limits (LOD and LOQ) of 6.14 fM and 11 fM, respectively, and demonstrated a wide linear range of 0.1 to 1000 pM. The assay showed high selectivity, good performance, and reliable repeatability and reproducibility, making it a promising method for rapidly and quantitatively detecting H. influenzae.

MICROCHIMICA ACTA (2023)

Review Chemistry, Analytical

Electrochemical-Based Sensing Platforms for Detection of Glucose and H2O2 by Porous Metal-Organic Frameworks: A Review of Status and Prospects

Hessamaddin Sohrabi et al.

Summary: This paper reviews the current progress in electrochemical detection using metal-organic frameworks (MOFs) for H2O2 and glucose recognition. It discusses the advantages of MOFs, such as straightforward procedure, high sensitivity, and economic prospects, as well as their potential applications in agricultural, water, and foodstuff samples.

BIOSENSORS-BASEL (2023)

Article Environmental Sciences

Bimetallic Fe/Mn MOFs/MβCD/AuNPs stabilized on MWCNTs for developing a label-free DNA-based genosensing bio-assay applied in the determination of Salmonella typhimurium in milk samples

Hessamaddin Sohrabi et al.

Summary: A genosensor based on innovative label-free DNA was developed for the detection of S. typhimurium in milk samples, using bimetallic Fe/Mn MOF and AuNPs stabilized on MWCNTs. Various characterization methods and electrochemical techniques were utilized, demonstrating excellent performance, specificity, and sensitivity.

CHEMOSPHERE (2022)

Article Environmental Sciences

A PCR-free genosensing platform for detection of Shigella dysenteriae in human plasma samples by porous and honeycomb-like biochar decorated with ultrathin flower-like MoS2 nanosheets incorporated with Au nanoparticles

Hessamaddin Sohrabi et al.

Summary: A gene detection platform was developed to detect Shigella dysenteriae in human plasma samples, incorporating biochar, MoS2 nanosheets, and Au nanoparticles. The platform demonstrated high selectivity and sensitivity, with LOD and LOQ values calculated under optimal conditions. The method also showed good repeatability and could be easily reused for subsequent detection assays, highlighting its potential for practical applications in genetic screening.

CHEMOSPHERE (2022)

Article Chemistry, Analytical

A label-free optical immunoassay based on birefringence of liquid crystal for insulin-like growth factor-I sensing

Jiamei Chen et al.

Summary: A label-free optical biosensor based on nematic liquid crystals (LCs) of 4-cyano-4-pentylbiphenyl (5CB) was developed for ultrasensitive detection of trace IGF-I in human serum samples. The biosensor showed high sensitivity with a detection limit of 1.0 ng/mL and a linear range of 10.0-2000.0 ng/mL. This method offers quick and accurate detection of IGF-I in a physiological range, providing valuable information for clinical diagnosis of GH-IGF-I axis related diseases.

SENSORS AND ACTUATORS B-CHEMICAL (2022)

Article Chemistry, Applied

Development and single laboratory validation of a targeted liquid chromatography-triple quadrupole mass spectrometry-based method for the determination of insulin like growth factor-1 in different types of milk samples

Giulia Remaggi et al.

Summary: A simple and reliable LC-MS/MS method was developed to accurately detect IGF-1 in milk samples. The method showed low detection limits, high precision, and accuracy, as validated using two biomarker peptides.

FOOD CHEMISTRY-X (2022)

Article Chemistry, Analytical

Label-free biosensor for trace insulin-like growth factor-I assay based on rGO-SnS2 heterostructure nanocomposite

Zhenping Liu et al.

Summary: A label-free electrochemical impedance biosensing platform was developed for detection of AgIGF-I using a nano-composite of reduced graphene oxide-tin sulfide loaded with gold nanoparticles. The biosensor showed high sensitivity and selectivity for IGF-I detection in human plasma samples, expanding the application of the nanocomposite in bioanalysis and clinical diagnosis.

SENSORS AND ACTUATORS B-CHEMICAL (2022)

Article Nanoscience & Nanotechnology

Gold-enhanced current-volt dielectrode junction for biosensing with an aptamer-insulin-like growth factor-1-antibody sandwich pattern

Lanbo Liu et al.

Summary: In this study, a highly sensitive IGF1 detection method was developed using a gold nanoparticle-enhanced dielectrode junctional sensing surface as a transducer. The aptamer-antibody sandwich assay allowed for the detection of different concentrations of IGF1 and selective detection of IGF1 in biological samples.

MATERIALS EXPRESS (2022)

Review Biochemistry & Molecular Biology

Recent developments in the structural characterisation of the IR and IGF1R: implications for the design of IR-IGF1R hybrid receptor modulators

Samuel J. Turvey et al.

Summary: This review discusses the advances in structural understanding of the insulin receptor (IR) and insulin-like growth factor 1 receptor (IGF1R) and the importance of designing small-molecule modulators to study the role of IR-IGF1R hybrid receptors in cell biology.

RSC MEDICINAL CHEMISTRY (2022)

Review Biochemistry & Molecular Biology

GH/IGF-1 Abnormalities and Muscle Impairment: From Basic Research to Clinical Practice

Betina Biagetti et al.

Summary: Impairment of skeletal muscle function is a major contributing factor to the poor quality of life in acromegaly (ACRO) patients, but the underlying mechanisms and treatment options are still limited. Although GH and IGF-1 levels are associated with ACRO myopathies, the exact effects attributed to increased GH or IGF-1 levels remain unclear. Further research on the role of GH and IGF-1 in muscle anabolism is necessary to improve our understanding.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Chemistry, Analytical

Nanoparticle-assisted sacrificial synthesis of hierarchical porous carbon composite for rapid sample enrichment and ultrasensitive label-free immunosensing of interleukin-6 biomarker

Zhenping Liu et al.

Summary: The study presents a rapid and ultrasensitive label-free electrochemical immunosensor for IL-6 detection using nanoporous mesoporous-carbon composite decorated with gold nanoparticles. The immunosensors demonstrate high sensitivity and selectivity with a linear dynamic range of 0.5-1200 pg mL(-1) and an ultralow limit of detection of 0.14 pg mL(-1). The biosensor shows potential for other biomarkers in point-of-care biosensing applications.

JOURNAL OF ELECTROANALYTICAL CHEMISTRY (2021)

Article Chemistry, Analytical

A novel engineered label-free Zn-based MOF/CMC/AuNPs electrochemical genosensor for highly sensitive determination of Haemophilus Influenzae in human plasma samples

Hessamaddin Sohrabi et al.

Summary: The novel label-free DNA genosensing assay developed in this study, based on Zn-based MOF and AuNPs surface modification, demonstrates high specificity and sensitivity for recognizing the H. influenza genome in human plasma samples. Various characterization techniques validated its performance, with LOD and LOQ under optimal conditions being 1.48 fM and 3.23 fM respectively, suitable for the determination of the L-fuculokinase gene.

MICROCHIMICA ACTA (2021)

Article Food Science & Technology

Electrospun Antibacterial and Antioxidant Zein/Polylactic Acid/Hydroxypropyl Methylcellulose Nanofibers as an Active Food Packaging System

Masoud Aman Mohammadi et al.

Summary: This study demonstrated the successful fabrication of zein/polylactic acid/hydroxypropyl methylcellulose nanofibers incorporating Zenian essential oil using the electrospinning method, showing good antioxidant and antibacterial properties. The incorporation of Zenian essential oil improved the thermal stability and tensile strength of the nanofibers, with no cell toxicity observed, indicating good biocompatibility for potential food packaging applications.

FOOD AND BIOPROCESS TECHNOLOGY (2021)

Article Chemistry, Analytical

An iron oxide nanoworm hybrid on an interdigitated microelectrode silica surface to detect abdominal aortic aneurysms

Guangjun Yan et al.

Summary: The research introduces a new sensing surface modified by iron oxide nanoworms for detecting the AAA biomarker insulin-like growth factor-1, achieving a specific and significant detection of IGF1 in the experiments.

MICROCHIMICA ACTA (2021)

Article Chemistry, Analytical

Isotopic Peak Index, Relative Retention Time, and Tandem MS for Automated High Throughput IGF-1 Variants Identification in a Clinical Laboratory

Ievgen Motorykin et al.

Summary: Measurements of insulin-like growth factor-1 (IGF-1) using LC-MS technology allow for accurate assessment and management of growth-related disorders through the identification of various IGF-1 variants. This approach provides a comprehensive profile of a patient's IGF-1 status and enables the exploration of genotype-phenotype relationships in IGF-1 variants.

ANALYTICAL CHEMISTRY (2021)

Review Cell Biology

Insulin/IGF-1 signaling promotes immunosuppression via the STAT3 pathway: impact on the aging process and age-related diseases

Antero Salminen et al.

Summary: The insulin/IGF-1 signaling pathway and STAT3 signaling pathway are closely related, playing important roles in immunosuppressive cells, inflammation, and cellular senescence. Excessive activation may promote the aging process by inducing insulin resistance and cellular senescence.

INFLAMMATION RESEARCH (2021)

Article Multidisciplinary Sciences

Ultrasensitive and label free electrochemical immunosensor for detection of ROR1 as an oncofetal biomarker using gold nanoparticles assisted LDH/rGO nanocomposite

Rozita Abolhasan et al.

Summary: A highly sensitive label-free electrochemical immunosensor based on NiFe-LDH/rGO/Au nanoparticles modified electrode was developed for the determination of ROR1, showing a sensitive response in the range of 0.01-1 pg mL(-1) and a lower limit of quantification of 10 ag mL(-1). The sensor exhibited good selectivity, reproducibility, and stability in the analysis of ROR1 in serum samples, providing acceptable results for chronic lymphocytic leukemia patients.

SCIENTIFIC REPORTS (2021)

Review Chemistry, Multidisciplinary

A review of recent progress in polymeric electrospun nanofiber membranes in addressing safe water global issues

T. M. Subrahmanya et al.

Summary: Electrospun nanofiber membranes (ENMs) have unique advantages in water treatment, such as high specific surface area and mechanical robustness, and show potential in environmental, energy, and health sectors. In recent years, the preparation technology of ENMs has been continuously improved, playing a positive role in solving the problems of traditional electrospinning, with many challenges in future development.

RSC ADVANCES (2021)

Article Polymer Science

Investigation of chemical bonding and electronic network of rGO/PANI/PVA electrospun nanofiber

W. Ishwarchand Singh et al.

Summary: Reduced graphene oxide-reinforced PVA/PANI/rGO nanofibers were synthesized and characterized for morphology, elemental composition, vibrational bonding, and optical properties, showing variations in the structural and electronic network of carbon with different rGO content.

POLYMER BULLETIN (2021)

Article Biochemistry & Molecular Biology

Aloe vera-loaded nanofibrous scaffold based on Zein/Polycaprolactone/Collagen for wound healing

Marjan Ghorbani et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Biochemistry & Molecular Biology

Improved immunoassay for Insulin-like Growth Factor 1 detection by aminated silica nanoparticle in ELISA

Xin Hong et al.

PROCESS BIOCHEMISTRY (2020)

Review Biochemistry & Molecular Biology

Role of Alternatively Spliced Messenger RNA (mRNA) Isoforms of the Insulin-Like Growth Factor 1 (IGF1) in Selected Human Tumors

Aldona Kasprzak et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Cell Biology

Role of the GH-IGF1 system in progression of cancer

Haim Werner et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2020)

Article Endocrinology & Metabolism

IGF1 for the diagnosis of growth hormone deficiency in children and adolescents: a reappraisal

Anastasia Ibba et al.

ENDOCRINE CONNECTIONS (2020)

Review Engineering, Biomedical

A review on recent advances in application of electrospun nanofiber materials as biosensors

Yanbo Liu et al.

CURRENT OPINION IN BIOMEDICAL ENGINEERING (2020)

Review Materials Science, Biomaterials

Reconstructing nanofibers from natural polymers using surface functionalization approaches for applications in tissue engineering, drug delivery and biosensing devices

Hasham S. Sofi et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2019)

Article Chemistry, Multidisciplinary

Silver sulfadiazine loaded zein nanofiber mats as a novel wound dressing

Sana Ullah et al.

RSC ADVANCES (2019)

Article Chemistry, Analytical

Influence of antibody immobilization strategy on carbon electrode immunoarrays

Mohamed Sharafeldin et al.

ANALYST (2019)

Review Biophysics

Label-free biosensors in the field of stem cell biology

Farzaneh Fathi et al.

BIOSENSORS & BIOELECTRONICS (2018)

Article Chemistry, Applied

Characterization of gelatin/zein nanofibers by hybrid electrospinning

Lingli Deng et al.

FOOD HYDROCOLLOIDS (2018)

Article Multidisciplinary Sciences

How ligand binds to the type 1 insulin-like growth factor receptor

Yibin Xu et al.

NATURE COMMUNICATIONS (2018)

Article Food Science & Technology

Properties of Encapsulated Fish Oil in Electrospun Zein Fibres Under Simulated In Vitro Conditions

Khalid Moomand et al.

FOOD AND BIOPROCESS TECHNOLOGY (2015)

Article Materials Science, Multidisciplinary

Electric field distribution and jet motion in electrospinning process: from needle to hole

Yuansheng Zheng et al.

JOURNAL OF MATERIALS SCIENCE (2013)

Article Endocrinology & Metabolism

Associations of IGF1 and its binding proteins with abdominal aortic aneurysm and aortic diameter in older men

Bu B. Yeap et al.

EUROPEAN JOURNAL OF ENDOCRINOLOGY (2012)

Article Polymer Science

Optimization of stabilization conditions for electrospun polyacrylonitrile nanofibers

Meiyu Wu et al.

POLYMER DEGRADATION AND STABILITY (2012)