Journal
THERANOSTICS
Volume 6, Issue 13, Pages 2488-2524Publisher
IVYSPRING INT PUBL
DOI: 10.7150/thno.16589
Keywords
Nanoparticles; chemistry; surface coating; persistent luminescence and in vivo imaging
Categories
Funding
- Region Ile de France [I07-876/R]
- European Community [CLINIGENE LSHB-CT-2006-018933]
- CNRS
- ANR Natlurim [ANR-08-NANO-025]
- ANR PEPSI [ANR-14-CE08-0016-01]
- PRES Sorbonne Paris Cite (Odiceo project)
- Biospace Lab
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Imaging nanoprobes are a group of nanosized agents developed for providing improved contrast for bioimaging. Among various imaging probes, optical sensors capable of following biological events or progresses at the cellular and molecular levels are actually actively developed for early detection, accurate diagnosis, and monitoring of the treatment of diseases. The optical activities of nanoprobes can be tuned on demand by chemists by engineering their composition, size and surface nature. This review will focus on researches devoted to the conception of nanoprobes with particular optical properties, called persistent luminescence, and their use as new powerful bioimaging agents in preclinical assays.
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