4.7 Article

Stretching the chains: the destabilizing impact of Cu2+ and Zn2+ ions on K48-linked diubiquitin

Related references

Note: Only part of the references are listed.
Review Cell Biology

Role of K63-linked ubiquitination in cancer

Liangzi Cao et al.

Summary: In this article, we summarize the molecular mechanisms of K63-linked ubiquitination in dictating different biological activities of tumors and highlight novel opportunities for future therapy targeting certain regulation of K63-linked ubiquitination in tumors.

CELL DEATH DISCOVERY (2022)

Review Biochemistry & Molecular Biology

Ubiquitin signalling in neurodegeneration: mechanisms and therapeutic opportunities

Marlene F. Schmidt et al.

Summary: Neurodegenerative diseases are characterized by progressive nervous system damage, such as the selective loss of vulnerable neurons, leading to motor symptoms and cognitive decline. The primary risk factor for these diseases is aging, which results in reduced proteasomal degradation and autophagy, leading to the accumulation of neurotoxic protein aggregates. Ubiquitin plays a critical role in both degradation pathways and non-degradative signaling, implicating it as a potential target for new drugs to treat neurodegenerative diseases.

CELL DEATH AND DIFFERENTIATION (2021)

Article Biochemistry & Molecular Biology

A Pentapeptide with Tyrosine Moiety as Fluorescent Chemosensor for Selective Nanomolar-Level Detection of Copper(II) Ions

Krzysztof Zamojc et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Pharmacology & Pharmacy

The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges

G. R. Tundo et al.

PHARMACOLOGY & THERAPEUTICS (2020)

Article Chemistry, Physical

Water-soluble Cu2+-fluorescent sensor based on core-substituted naphthalene diimide and its application in drinking water analysis and live cell imaging

Panida Praikaew et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY (2019)

Review Biochemistry & Molecular Biology

Repurposing of Copper(II)-chelating Drugs for the Treatment of Neurodegenerative Diseases

Valeria Lanza et al.

CURRENT MEDICINAL CHEMISTRY (2018)

Article Biochemical Research Methods

Ab initio electron density determination directly from solution scattering data

Thomas D. Grant

NATURE METHODS (2018)

Article Biochemical Research Methods

CHROMIXS: automatic and interactive analysis of chromatography-coupled small-angle X-ray scattering data

Alejandro Panjkovich et al.

BIOINFORMATICS (2018)

Article Chemistry, Multidisciplinary

Processing two-dimensional X-ray diffraction and small-angle scattering data in DAWN 2

J. Filik et al.

JOURNAL OF APPLIED CRYSTALLOGRAPHY (2017)

Article Biochemistry & Molecular Biology

Comparison of native and non-native ubiquitin oligomers reveals analogous structures and reactivities

Grace H. Pham et al.

PROTEIN SCIENCE (2016)

Article Multidisciplinary Sciences

Copper(II) ions affect the gating dynamics of the 20S proteasome: a molecular and in cell study

Anna Maria Santoro et al.

SCIENTIFIC REPORTS (2016)

Article Chemistry, Multidisciplinary

The fluorescence regulation mechanism of the paramagnetic metal in a biological HNO sensor

Wenjing Yang et al.

CHEMICAL COMMUNICATIONS (2015)

Article Biochemistry & Molecular Biology

SASBDB, a repository for biological small-angle scattering data

Erica Valentini et al.

NUCLEIC ACIDS RESEARCH (2015)

Article Chemistry, Multidisciplinary

RootProf: software for multivariate analysis of unidimensional profiles

Rocco Caliandro et al.

JOURNAL OF APPLIED CRYSTALLOGRAPHY (2014)

Article Chemistry, Multidisciplinary

Conformational Selection of Ubiquitin Quaternary Structures Driven by Zinc Ions

Simona Fermani et al.

CHEMISTRY-A EUROPEAN JOURNAL (2013)

Article Chemistry, Inorganic & Nuclear

Inorganic Stressors of Ubiquitin

Giuseppe Arena et al.

INORGANIC CHEMISTRY (2013)

Review Biochemistry & Molecular Biology

Ubiquitin-Binding Proteins: Decoders of Ubiquitin-Mediated Cellular Functions

Koraljka Husnjak et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 81 (2012)

Review Biochemistry & Molecular Biology

The Ubiquitin Code

David Komander et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 81 (2012)

Review Chemistry, Multidisciplinary

Bioinorganic Chemistry of Alzheimer's Disease

Kasper P. Kepp

CHEMICAL REVIEWS (2012)

Review Chemistry, Inorganic & Nuclear

New fluorescent chemosensors for metal ions in solution

Mauro Formica et al.

COORDINATION CHEMISTRY REVIEWS (2012)

Software Review Chemistry, Multidisciplinary

New developments in the ATSAS program package for small-angle scattering data analysis

Maxim V. Petoukhov et al.

JOURNAL OF APPLIED CRYSTALLOGRAPHY (2012)

Review Biochemistry & Molecular Biology

Applications of pressure perturbation calorimetry in biophysical studies

Yong Zhai et al.

BIOPHYSICAL CHEMISTRY (2011)

Article Chemistry, Multidisciplinary

Crystallographic Analysis of Metal-Ion Binding to Human Ubiquitin

Fabio Arnesano et al.

CHEMISTRY-A EUROPEAN JOURNAL (2011)

Article Chemistry, Multidisciplinary

Zinc(II) Complexes of Ubiquitin: Speciation, Affinity and Binding Features

Giuseppe Arena et al.

CHEMISTRY-A EUROPEAN JOURNAL (2011)

Article Biochemistry & Molecular Biology

Conformational Dynamics of Wild-type Lys-48-linked Diubiquitin in Solution

Takashi Hirano et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

An Inhibitor of a Deubiquitinating Enzyme Regulates Ubiquitin Homeostasis

Yoko Kimura et al.

Software Review Chemistry, Multidisciplinary

DAMMIF, a program for rapid ab-initio shape determination in small-angle scattering

Daniel Franke et al.

JOURNAL OF APPLIED CRYSTALLOGRAPHY (2009)

Article Biochemistry & Molecular Biology

Suppression of the Deubiquitinating Enzyme USP5 Causes the Accumulation of Unanchored Polyubiquitin and the Activation of p53

Saurabh Dayal et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Chemistry, Multidisciplinary

Coumarin-Derived Cu2+-Selective Fluorescence Sensor: Synthesis, Mechanisms, and Applications in Living Cells

Hyo Sung Jung et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)

Article Multidisciplinary Sciences

Direct activation of protein kinases by unanchored polyubiquitin chains

Zong-Ping Xia et al.

NATURE (2009)

Review Cell Biology

Breaking the chains: structure and function of the deubiquitinases

David Komander et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)

Article Multidisciplinary Sciences

Copper-Triggered Aggregation of Ubiquitin

Fabio Arnesano et al.

PLOS ONE (2009)

Article Biochemistry & Molecular Biology

Flexible fitting of atomic structures into electron microscopy maps using molecular dynamics

Leonardo G. Trabuco et al.

STRUCTURE (2008)

Article Biochemistry & Molecular Biology

Ubiquitin is degraded by the ubiquitin system as a monomer and as part of its conjugated target

Nitzan Shabek et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)

Review Biochemistry & Molecular Biology

Inference of macromolecular assemblies from crystalline state

Evgeny Krissinel et al.

JOURNAL OF MOLECULAR BIOLOGY (2007)

Article Chemistry, Multidisciplinary

Ubiquitin stability and the Lys63-linked polyubiquitination site are compromised on copper binding

Danilo Milardi et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2007)

Article Biochemistry & Molecular Biology

Interdomain mobility in Di-ubiquitin revealed by NMR

Yaroslav Ryabov et al.

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2006)

Review Chemistry, Multidisciplinary

Scalable molecular dynamics with NAMD

JC Phillips et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2005)

Article Chemistry, Multidisciplinary

PRIMUS:: a Windows PC-based system for small-angle scattering data analysis

PV Konarev et al.

JOURNAL OF APPLIED CRYSTALLOGRAPHY (2003)

Article Chemistry, Multidisciplinary

Uniqueness of ab initio shape determination in small-angle scattering

VV Volkov et al.

JOURNAL OF APPLIED CRYSTALLOGRAPHY (2003)

Article Biochemistry & Molecular Biology

Effect of neurotoxic metal ions on the proteolytic activities of the 20S proteasome from bovine brain

M Amici et al.

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2002)

Article Clinical Neurology

Oxidative damage is the earliest event in Alzheimer disease

A Nunomura et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2001)

Article Chemistry, Multidisciplinary

Automated matching of high- and low-resolution structural models

MB Kozin et al.

JOURNAL OF APPLIED CRYSTALLOGRAPHY (2001)