Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 21, Issue 35, Pages 7090-7094Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d3ob01176c
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The simple and scalable electrochemical oxidation of the electron-rich benzene ring, followed by intramolecular capture of reactive cation-radical intermediates, enables the synthesis of spirocyclic morpholines and tetrahydrofurans. The obtained molecules can be easily modified into valuable building blocks.
Simple and scalable electrochemical oxidation of the electron-rich benzene ring followed by intramolecular capture of reactive cation-radical intermediates opens access to spirocyclic morpholines and tetrahydrofurans. The obtained molecules can be readily modified to value-added building blocks.
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