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Pharmacodynamics of mycophenolate mofetil after nonmyeloablative conditioning and unrelated donor hematopoietic cell transplantation
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BLOOD (2005)
Pharmacokinetics of sirolimus (rapamycin) in subjects with mild to moderate hepatic impairment
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JOURNAL OF CLINICAL PHARMACOLOGY (2005)
Relationship of mycophenolic acid exposure to clinical outcome after hematopoietic cell transplantation
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CLINICAL PHARMACOLOGY & THERAPEUTICS (2005)
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An investigation of human and rat liver microsomal mycophenolic acid glucuronidation: Evidence for a principal role of UGT1A enzymes and species differences in UGT1A specificity
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DRUG METABOLISM AND DISPOSITION (2005)
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EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2005)
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BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2005)
A phase I/II study of mycophenolate mofetil in combination with cyclosporine for prophylaxis of acute graft-versus-host disease after myeloablative conditioning and allogeneic hematopoietic cell transplantation
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BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2005)
Control of advanced and refractory acute myelogenous leukaemia with sirolimus-based non-myeloablative allogeneic stem cell transplantation
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BRITISH JOURNAL OF HAEMATOLOGY (2005)
Cyclosporine A and Mycophenolate Mofetil vs Cyclosporine A and Methotrexate for graft-versus-host disease prophylaxis after stem cell transplantation from HLA-identical siblings
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BONE MARROW TRANSPLANTATION (2005)
Cyclosporine interacts with mycophenolic acid by inhibiting the multidrug resistance-associated protein 2
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AMERICAN JOURNAL OF TRANSPLANTATION (2005)
The influence of norfloxacin and metronidazole on the disposition of mycophenolate mofetil
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JOURNAL OF CLINICAL PHARMACOLOGY (2005)
Population pharmacokinetics of mycophenolic acid in renal transplant recipients
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CLINICAL PHARMACOKINETICS (2005)
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CLINICAL PHARMACOKINETICS (2005)
Identification of the UDP-glucuronosyltransferase isoforms involved in mycophenolic acid phase II metabolism
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DRUG METABOLISM AND DISPOSITION (2005)
Rapamycin (sirolimus) for treatment of chronic graft-versus-host disease
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BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2005)
Short sirolimus half-life in pediatric renal transplant recipients on a calcineurin inhibitor-free protocol
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PEDIATRIC TRANSPLANTATION (2004)
A pilot study of tacrolimus and mycophenolate mofetil graft-versus-host disease prophylaxis in childhood and adolescent allogeneic stem cell transplant recipients
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BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2004)
Randomized long-term trial of tacrolimus/sirolimus versus tacrolimus/mycophenolate mofetil versus cyclosporine (Neoral)/sirolimus in renal transplantation. II. Survival, function, and protocol compliance at 1 year
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TRANSPLANTATION (2004)
A randomized long-term trial of tacrolimus and sirolimus versus tacrolimus and mycophenolate mofetil versus cyclosporine (Neoral) and sirolimus in renal transplantation. I. Drug interactions and rejection at one year
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TRANSPLANTATION (2004)
Sirolimus for GVHD prophylaxis in allogeneic stem cell transplantation
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BONE MARROW TRANSPLANTATION (2004)
The main role of UGT1A9 in the hepatic metabolism of mycophenolic acid and the effects of naturally occurring variants
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DRUG METABOLISM AND DISPOSITION (2004)
Pre-transplant inosine monophosphate dehydrogenase activity is associated with clinical outcome after renal transplantation
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AMERICAN JOURNAL OF TRANSPLANTATION (2004)
HLA matching in allogeneic stem cell transplantation
EW Petersdorf
CURRENT OPINION IN HEMATOLOGY (2004)
Cyclosporin A, but not tacrolimus, inhibits the biliary excretion of mycophenolic acid glucuronide possibly mediated by multidrug resistance-associated protein 2 in rats
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JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)
A prospective randomized trial comparing cyclosporine and short course methotrexate with cyclosporine and mycophenolate mofetil for GVHD prophylaxis in myeloablative allogeneic bone marrow transplantation
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BONE MARROW TRANSPLANTATION (2004)
Pharmacokinetics of sirolimus and tacrolimus in pediatric transplant patients
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AMERICAN JOURNAL OF TRANSPLANTATION (2004)
Relationship between CsA trough blood concentration and severity of acute graft-versus-host disease after paediatric stem cell transplantation from matched-sibling or unrelated donors
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BONE MARROW TRANSPLANTATION (2003)
Twelve-month evaluation of the clinical pharmacokinetics of total and free mycophenolic acid and its glucuronide metabolites in renal allograft recipients on low dose tacrolimus in combination with mycophenolate mofetil
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THERAPEUTIC DRUG MONITORING (2003)
HLA-matched unrelated donor hematopoietic cell transplantation after nonmyeloablative conditioning for patients with hematologic malignancies
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BLOOD (2003)
Sirolimus, tacrolimus, and low-dose methotrexate for graft-versus-host disease prophylaxis in mismatched related donor or unrelated donor transplantation
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BLOOD (2003)
Population pharmacokinetic analysis of mycophenolic acid in renal transplant recipients following oral administration of mycophenolate mofetil
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BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2003)
Pharmacokinetics and pharmacodynamics of anti-thymocyte globulin in recipients of partially HLA-matched blood hematopoietic progenitor cell transplantation
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BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2003)
Pharmacokinetics of alemtuzumab used for in vivo and in vitro T-cell depletion in allogeneic transplantations: relevance for early adoptive immunotherapy and infectious complications
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BLOOD (2003)
Superior T-cell suppression by rapamycin and FK506 over rapamycin and cyclosporine a because of abrogated cytotoxic T-lymphocyte induction, impaired memory responses, and persistent apoptosis
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TRANSPLANTATION (2003)
Sirolimus: Its discovery, biological properties, and mechanism of action
SN Sehgal
TRANSPLANTATION PROCEEDINGS (2003)
An integrated metabonomic investigation of acetaminophen toxicity in the mouse using NMR spectroscopy
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CHEMICAL RESEARCH IN TOXICOLOGY (2003)
Low-dose total body irradiation (TBI) and fludarabine followed by hematopoietic cell transplantation (HCT) from HLA-matched or mismatched unrelated donors and postgrafting immunosuppression with cyclosporine and mycophenolate mofetil (MNF) can induce durable complete chimerism and sustained remissions in patients with hematological diseases
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BLOOD (2003)
Allergic skin and systemic reactions in a patient with pure red cell aplasia and anti-erythropoietin antibodies challenged with different epoetins
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JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2002)
Metabonomics: a platform for studying drug toxicity and gene function
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NATURE REVIEWS DRUG DISCOVERY (2002)
Sirolimus (rapamycin) for the treatment of steroid-refractory acute graft-versus-host disease
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TRANSPLANTATION (2001)
Antithymocyte globulin for graft-versus-host disease prophylaxis in transplants from unrelated donors: 2 randomized studies from Gruppo Italiano Trapianti Midollo Osseo (GITMO)
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BLOOD (2001)
Improved clinical outcome of paediatric bone marrow recipients using a test dose and Bayesian pharmacokinetic individualization of busulfan dosage regimens
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BONE MARROW TRANSPLANTATION (2001)
Total and active thymoglobulin levels: effects of dose and sensitization on serum concentrations
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TRANSPLANT IMMUNOLOGY (2001)
Hematopoietic cell transplantation in older patients with hematologic malignancies: replacing high-dose cytotoxic therapy with graft-versus-tumor effects
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BLOOD (2001)
Pharmacokinetics of intravenous mycophenolate mofetil after allogeneic blood stem cell transplantation
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CLINICAL TRANSPLANTATION (2001)
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CLINICAL PHARMACOKINETICS (2001)
Effects of obesity on pharmacokinetics - Implications for drug therapy
G Cheymol
CLINICAL PHARMACOKINETICS (2000)
Development and application of a high-performance liquid chromatography-based assay for determination of the activity of inosine 5′-monophosphate dehydrogenase in whole blood and isolated mononuclear cells
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THERAPEUTIC DRUG MONITORING (2000)
Mycophenolate mofetil for the prophylaxis of acute GVHD in HLA-mismatched bone marrow transplant patients
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CLINICAL TRANSPLANTATION (2000)
Mycophenolate mofetil in stem cell transplant patients in relation to plasma level of active metabolite
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CLINICAL BIOCHEMISTRY (2000)
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