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JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Dynamics of insulin secretion and the clinical implications for obesity and diabetes
Susumu Seino et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Emerging roles for the BAI1 protein family in the regulation of phagocytosis, synaptogenesis, neurovasculature, and tumor development
Sarah M. Cork et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2011)
Signaling diversity of PKA achieved via a Ca2+-cAMP-PKA oscillatory circuit
Qiang Ni et al.
NATURE CHEMICAL BIOLOGY (2011)
The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins
Marc F. Bolliger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Soluble epoxide hydrolase deficiency alters pancreatic islet size and improves glucose homeostasis in a model of insulin resistance
Ayala Luria et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Effects of glucagon-like peptide 1 on glycemia control and its metabolic consequence after severe thermal injury-studies in an animal model
Chuan-an Shen et al.
SURGERY (2011)
Phospholipase C-ε links Epac2 activation to the potentiation of glucose-stimulated insulin secretion from mouse islets of Langerhans
Igor Dzhura et al.
ISLETS (2011)
PKA-dependent potentiation of glucose-stimulated insulin secretion by Epac activator 8-pCPT-2′-O-Me-cAMP-AM in human islets of Langerhans
Oleg G. Chepurny et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2010)
Exocytosis mechanisms underlying insulin release and glucose uptake: conserved roles for Munc18c and syntaxin 4
Jenna L. Jewell et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2010)
Epac: Defining a New Mechanism for cAMP Action
Martijn Gloerich et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2010)
New evidence for a role of melatonin in glucose regulation
Elmar Peschke et al.
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM (2010)
GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects
Da Young Oh et al.
CELL (2010)
Rim2α Determines Docking and Priming States in Insulin Granule Exocytosis
Takao Yasuda et al.
CELL METABOLISM (2010)
Sphingolipids and insulin resistance: the five Ws
Scott A. Summers
CURRENT OPINION IN LIPIDOLOGY (2010)
The Prostacyclin Analog Beraprost Sodium Ameliorates Characteristics of Metabolic Syndrome in Obese Zucker (Fatty) Rats
Nahoko Sato et al.
DIABETES (2010)
β-Cell Failure in Diet-Induced Obese Mice Stratified According to Body Weight Gain: Secretory Dysfunction and Altered Islet Lipid Metabolism Without Steatosis or Reduced β-Cell Mass
Marie-Line Peyot et al.
DIABETES (2010)
Increased CYP2J3 Expression Reduces Insulin Resistance in Fructose-Treated Rats and db/db Mice
Xizhen Xu et al.
DIABETES (2010)
cAMP Mediators of Pulsatile Insulin Secretion from Glucose-stimulated Single β-Cells
Olof Idevall-Hagren et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Pancreas-specific Gsα deficiency has divergent effects on pancreatic α- and β-cell proliferation
Tao Xie et al.
JOURNAL OF ENDOCRINOLOGY (2010)
Inhibition or Deletion of Soluble Epoxide Hydrolase Prevents Hyperglycemia, Promotes Insulin Secretion, and Reduces Islet Apoptosis
Pengcheng Luo et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)
A multi-stage multi-design strategy provides strong evidence that the BAI3 locus is associated with early-onset venous thromboembolism
G. Antoni et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2010)
Blockage of ceramide metabolism exacerbates palmitate inhibition of pro-insulin gene expression in pancreatic β-cells
Jun Guo et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2010)
Molecular Mechanism of Calcium Channel Regulation in the Fight-or-Flight Response
Matthew D. Fuller et al.
SCIENCE SIGNALING (2010)
Transcriptional Regulation of Glucose Sensors in Pancreatic beta-Cells and Liver: An Update
Jin-Sik Bae et al.
SENSORS (2010)
Selecting GLP-1 agonists in the management of type 2 diabetes: differential pharmacology and therapeutic benefits of liraglutide and exenatide
Jonathan Pinkney et al.
THERAPEUTICS AND CLINICAL RISK MANAGEMENT (2010)
Rescuing the Subprime Meltdown in Insulin Exocytosis in Diabetes
Edwin P. Kwan et al.
MECHANISMS OF EXOCYTOSIS (2009)
An Open Access Database of Genome-wide Association Results
Andrew D. Johnson et al.
BMC MEDICAL GENETICS (2009)
Phospholipase A2 Biochemistry
John E. Burke et al.
CARDIOVASCULAR DRUGS AND THERAPY (2009)
Plasma Ceramides Are Elevated in Obese Subjects With Type 2 Diabetes and Correlate With the Severity of Insulin Resistance
Jacob M. Haus et al.
DIABETES (2009)
Munc18c Depletion Selectively Impairs the Sustained Phase of Insulin Release
Eunjin Oh et al.
DIABETES (2009)
From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus
Ralph A. DeFronzo
DIABETES (2009)
Functional pancreatic beta-cell mass: Involvement in type 2 diabetes and therapeutic intervention
M. Karaca et al.
DIABETES & METABOLISM (2009)
Oral Disposition Index Predicts the Development of Future Diabetes Above and Beyond Fasting and 2-h Glucose Levels
Kristina M. Utzschneider et al.
DIABETES CARE (2009)
Skeletal Muscle Insulin Resistance Is the Primary Defect in Type 2 Diabetes
Ralph A. DeFronzo et al.
DIABETES CARE (2009)
Regulation of insulin secretion: a matter of phase control and amplitude modulation (Reprinted)
J. C. Henquin
DIABETOLOGIA (2009)
Forkhead Box O1/Pancreatic and Duodenal Homeobox 1 Intracellular Translocation Is Regulated by c-Jun N-Terminal Kinase and Involved in Prostaglandin E2-Induced Pancreatic β-Cell Dysfunction
Zhuoxian Meng et al.
ENDOCRINOLOGY (2009)
Glucose Controls Cytosolic Ca2+ and Insulin Secretion in Mouse Islets Lacking Adenosine Triphosphate-Sensitive K+ Channels Owing to a Knockout of the Pore-Forming Subunit Kir6.2
Magalie A. Ravier et al.
ENDOCRINOLOGY (2009)
Mechanisms of biphasic insulin-granule exocytosis - roles of the cytoskeleton, small GTPases and SNARE proteins
Zhanxiang Wang et al.
JOURNAL OF CELL SCIENCE (2009)
Critical Role of the N-Terminal Cyclic AMP-Binding Domain of Epac2 in Its Subcellular Localization and Function
Manabu Niimura et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2009)
Phospholipase A2 structure/function, mechanism, and signaling
John E. Burke et al.
JOURNAL OF LIPID RESEARCH (2009)
Mammalian patatin domain containing proteins: a family with diverse lipolytic activities involved in multiple biological functions
Petra C. Kienesberger et al.
JOURNAL OF LIPID RESEARCH (2009)
Are all n-3 polyunsaturated fatty acids created equal?
Breanne M. Anderson et al.
LIPIDS IN HEALTH AND DISEASE (2009)
12/15-Lipoxygenase Is Required for the Early Onset of High Fat Diet-Induced Adipose Tissue Inflammation and Insulin Resistance in Mice
Dorothy D. Sears et al.
PLOS ONE (2009)
The cAMP Sensor Epac2 Is a Direct Target of Antidiabetic Sulfonylurea Drugs
Chang-Liang Zhang et al.
SCIENCE (2009)
Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2β in pancreatic β-cells and in iPLA2β-null mice
Shunzhong Bao et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2008)
12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by western diet
Craig S. Nunemaker et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2008)
Molecular, biochemical and functional characterizations of C1q/TNF family members: adipose-tissue-selective expression patterns, regulation by PPAR-gamma agonist, cysteine-mediated oligomerizations, combinatorial associations and metabolic functions
G. William Wong et al.
BIOCHEMICAL JOURNAL (2008)
GPR119, a novel G protein-coupled receptor target for the treatment of type 2 diabetes and obesity
H. A. Overton et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Glucose-induced cyclic AMP oscillations regulate pulsatile insulin secretion
Oleg Dyachok et al.
CELL METABOLISM (2008)
Palmitate impairs and eieosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets
Toyonori Kato et al.
DIABETES (2008)
Voltage-gated ion channels in human pancreatic β-cells:: Electrophysiological characterization and role in insulin secretion
Matthias Braun et al.
DIABETES (2008)
Ceramide: a contributor to insulin resistance or an innocent bystander?
G. Boden
DIABETOLOGIA (2008)
Calcium-independent Phospholipase A2 (iPLA2β)-mediated Ceramide Generation Plays a Key Role in the Cross-talk between the Endoplasmic Reticulum (ER) and Mitochondria during ER Stress-induced Insulin-secreting Cell Apoptosis
Xiaoyong Lei et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Regulation of Islet Hormone Release and Gastric Emptying by Endogenous Glucagon-Like Peptide 1 after Glucose Ingestion
Marzieh Salehi et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)
Role of the cAMP sensor Epac as a determinant of KATP channel ATP sensitivity in human pancreatic β-cells and rat INS-1 cells
Guoxin Kang et al.
JOURNAL OF PHYSIOLOGY-LONDON (2008)
Characterization of the mouse pancreatic islet proteome and comparative analysis with other mouse tissues
Vladislav A. Petyuk et al.
JOURNAL OF PROTEOME RESEARCH (2008)
Imaging Cyclic AMP Changes in Pancreatic Islets of Transgenic Reporter Mice
Joung Woul Kim et al.
PLOS ONE (2008)
Gαz negatively regulates insulin secretion and glucose clearance
Michelle E. Kimple et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Essential role of Epac2/Rap1 signaling in regulation of insulin granule dynamics by CAMP
Tadao Shibasaki et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Identification of type 2 diabetes genes in Mexican Americans through genome-wide association studies
M. Geoffrey Hayes et al.
DIABETES (2007)
Increased skeletal muscle ceramide level in men at risk of developing type 2 diabetes
M. Straczkowski et al.
DIABETOLOGIA (2007)
Arachidonic acid signaling is of imidazoline-induced KATP involved in the mechanism channel-independent stimulation of insulin secretion
V. V. Sharoyko et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2007)
Activation of exchange protein directly activated by cyclic adenosine monophosphate and protein kinase A regulate common and distinct steps in promoting plasma membrane exocytic and granule-to-granule fusions in rat islet β cells
Edwin P. Kwan et al.
PANCREAS (2007)
The group VIA calcium-independent phospholipase A2 participates in ER stress-induced INS-1 insulinoma cell apoptosis by promoting ceramide generation via hydrolysis of sphingomyelins by neutral Sphingomyelinase
Xiaoyong Lei et al.
BIOCHEMISTRY (2007)
Imaging analysis reveals mechanistic differences between first- and second-phase insulin exocytosis
Mica Ohara-Imaizumi et al.
JOURNAL OF CELL BIOLOGY (2007)
Inhibiting glycosphingolipid synthesis improves glycemic control and insulin sensitivity in animal models of type 2 diabetes
Hongmei Zhao et al.
DIABETES (2007)
Interleukin-1-receptor antagonist in type 2 diabetes mellitus
Claus M. Larsen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2007)
Modulation of the pancreatic islet β-cell-delayed rectifier potassium channel Kv2.1 by the polyunsaturated fatty acid arachidonate
David A. Jacobson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance
William L. Holland et al.
CELL METABOLISM (2007)
Progressive loss of β-cell function leads to worsening glucose tolerance in first-degree relatives of subjects with type 2 diabetes
Miriam Cnop et al.
DIABETES CARE (2007)
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
Carey N. Lumeng et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Prostaglandin E2 regulates Foxo activity via the Akt pathway:: implications for pancreatic islet beta cell dysfunction
Z. X. Meng et al.
DIABETOLOGIA (2006)
The phospholipase A2 superfamily and its group numbering system
Ralph H. Schaloske et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2006)
Imaging docking and fusion of insulin granules induced by antidiabetes agents - Sulfonylurea and glinide drugs preferentially mediate the fusion of newcomer, but not previously docked, insulin granules
Shinya Nagamatsu et al.
DIABETES (2006)
Sphingosine 1-phosphate affects cytokine-induced apoptosis in rat pancreatic islet β-cells
Suzanne G. Laychock et al.
ENDOCRINOLOGY (2006)
Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance
Nozomu Kamei et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Characterization of the human patatin-like phospholipase family
Paul A. Wilson et al.
JOURNAL OF LIPID RESEARCH (2006)
Insulin secretory responses and phospholipid composition of pancreatic islets from mice that do not express Group VIA phospholipase A2 and effects of metabolic stress on glucose homeostasis
Shunzhong Bao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Differential modulation of Cav1.2 and Cav1.3-Mediated glucose-stimulated insulin secretion by cAMP in INS-1 cells:: distinct roles for exchange protein directly activated by cAMP 2 (Epac2) and protein kinase A
Guohong Liu et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Expression of the gene for a membrane-bound fatty acid receptor in the pancreas and islet cell tumours in humans: evidence for GPR40 expression in pancreatic beta cells and implications for insulin secretion
T Tomita et al.
DIABETOLOGIA (2006)
Insulin secretion and action in subjects with impaired fasting glucose and impaired glucose tolerance - Results from the veterans administration genetic epidemiology study
MA Abdul-Ghani et al.
DIABETES (2006)
Inhibition of glucose-stimulated activation of extracellular signal-regulated protein kinases 1 and 2 by epinephrine in pancreatic β-cells
TB Gibson et al.
DIABETES (2006)
The natural course of β-cell function in nondiabetic and diabetic individuals -: The insulin resistance atherosclerosis study
A Festa et al.
DIABETES (2006)
Involvement of group VIA calcium-independent phospholipase A2 in macrophage engulfment of hydrogen peroxide-treated U937 cells
R Pérez et al.
JOURNAL OF IMMUNOLOGY (2006)
Structure of the cyclic-AMP-responsive exchange factor Epac2 in its auto-inhibited state
H Rehmann et al.
NATURE (2006)
In vivo and in vitro glucose-induced biphasic insulin secretion in the mouse -: Pattern and role of cytoplasmic Ca2+ and amplification signals in β-cells
JC Henquin et al.
DIABETES (2006)
CCR2 modulates inflammatory and metabolic effects of high-fat feeding
SP Weisberg et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Glucose-dependent increase in mitochondrial membrane potential, but not cytoplasmic calcium, correlates with insulin secretion in single islet cells
E Heart et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2006)
PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis
S Seino et al.
PHYSIOLOGICAL REVIEWS (2005)
A role for Gz in pancreatic islet β-cell biology
ME Kimple et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
A Munc13/RIM/Rab3 tripartite complex:: from priming to plasticity?
I Dulubova et al.
EMBO JOURNAL (2005)
Genetic and pharmacologic evidence that calcium-independent phospholipase A2β regulates virus-induced inducible nitric-oxide synthase expression by macrophages
JM Moran et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
A cAMP and Ca2+ coincidence detector in support of Ca2+-induced Ca2+ release in mouse pancreatic β cells
GX Kang et al.
JOURNAL OF PHYSIOLOGY-LONDON (2005)
Dietary-fat-induced obesity in mice results in beta cell hyperplasia but not increased insulin release: evidence for specificity of impaired beta cell adaptation
R Hull et al.
DIABETOLOGIA (2005)
Sphingosine kinase activity and sphingosine-1 phosphate production in rat pancreatic islets and INS-1 cells - Response to cytokines
LD Mastrandrea et al.
DIABETES (2005)
Distinct effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 on insulin secretion and gut motility
T Miki et al.
DIABETES (2005)
Decreased epoxygenase and increased epoxide hydrolase expression in the mesenteric artery of obese Zucker rats
XY Zhao et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2005)
beta-cell function in subjects spanning the range from normal glucose tolerance to overt diabetes: A new analysis
E Ferrannini et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2005)
Predictors of and longitudinal changes in insulin sensitivity and secretion preceding onset of type 2 diabetes
V Lyssenko et al.
DIABETES (2005)
Uncoupling of nutrient metabolism from insulin secretion by overexpression of cytosolic phospholipase A(2)
HM Milne et al.
DIABETES (2005)
Expression of voltage-gated potassium channels in human and rhesus pancreatic islets
LZ Yan et al.
DIABETES (2004)
β-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes
RP Robertson et al.
DIABETES (2004)
The role of cytosolic phospholipase A2 in insulin secretion
PM Jones et al.
DIABETES (2004)
Arachidonic acid, palmitic acid and glucose are important for the modulation of clonal pancreatic β-cell insulin secretion, growth and functional integrity
G Dixon et al.
CLINICAL SCIENCE (2004)
Both triggering and amplifying pathways contribute to fuel-induced insulin secretion in the absence of sulfonylurea receptor-1 in pancreatic β-cells
M Nenquin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Free fatty acid-induced β-cell defects are dependent on uncoupling protein 2 expression
JW Joseph et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Protein kinase activation increases insulin secretion by sensitizing the secretory machinery to Ca2+
QF Wan et al.
JOURNAL OF GENERAL PHYSIOLOGY (2004)
Expression of brain-specific angiogenesis inhibitor 3 (BAI3) in normal brain and implications for BAI3 in ischemia-induced brain angiogenesis and malignant glioma
HJ Kee et al.
FEBS LETTERS (2004)
Pathways in β-cell stimulus-secretion coupling as targets for therapeutic insulin secretagogues
JC Henquin
DIABETES (2004)
Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities
CM Jenkins et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Epac: A new cAMP-binding protein in support of glucagon-like peptide-1 receptor-mediated signal transduction in the pancreatic beta-cell
GG Holz
DIABETES (2004)
Ceramide content is increased in skeletal muscle from obese insulin-resistant humans
JM Adams et al.
DIABETES (2004)
Ca2+-induced Ca2+ release via inositol 1,4,5-trisphosphate receptors is amplified by protein kinase A and triggers exocytosis in pancreatic β-cells
O Dyachok et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The expression and function of a group VIA calcium-independent phospholipase A2 (iPLA2β) in β-cells
J Turk et al.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2004)
Antagonism of rat β-cell voltage-dependent K+ currents by exendin 4 requires dual activation of the cAMP/protein kinase A and phosphatidylinositol 3-kinase signaling pathways
PE MacDonald et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Pancreatic islets and insulinoma cells express a novel isoform of group VIA phospholipase A2 (iPLA2β) that participates in glucose-stimulated insulin secretion and is not produced by alternate splicing of the iPLA2β transcript
S Ramanadham et al.
BIOCHEMISTRY (2003)
Type VIII adenylyl cyclase in rat beta cells: coincidence signal detector/generator for glucose and GLP-1
D Delmeire et al.
DIABETOLOGIA (2003)
Glucose regulates the cortical actin network through modulation of Cdc42 cycling to stimulate insulin secretion
AK Nevins et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2003)
Insulin granule dynamics in pancreatic beta cells
P Rorsman et al.
DIABETOLOGIA (2003)
Voltage-dependent K+ channels in pancreatic beta cells:: Role, regulation and potential as therapeutic targets
PE MacDonald et al.
DIABETOLOGIA (2003)
CAMP promotes pancreatic β-cell survival via CREB-mediated induction of IRS2
US Jhala et al.
GENES & DEVELOPMENT (2003)
cPLA2α-evoked formation of arachidonic acid and lysophospholipids is required for exocytosis in mouse pancreatic β-cells
K Juhl et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2003)
Monocyte chemoattractant protein 1 in obesity and insulin resistance
P Sartipy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Free fatty acids regulate insulin secretion from pancreatic β cells through GPR40
Y Itoh et al.
NATURE (2003)
Epac-selective cAMP analog 8-pCPT-2′-O-Me-cAMP as a stimulus for Ca2+-induced Ca2+ release and exocytosis in pancreatic β-cells
GX Kang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
SUR1 regulates PKA-independent cAMP-induced granule priming in mouse pancreatic B-cells
L Eliasson et al.
JOURNAL OF GENERAL PHYSIOLOGY (2003)
A human cell surface receptor activated by free fatty acids and thiazolidinedione drugs
K Kotarsky et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Obesity is associated with macrophage accumulation in adipose tissue
SP Weisberg et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Section 5:: β-cell stimulus-secretion coupling:: Hormonal and pharmacological modulators -: Insulin receptor signaling and sarco/endoplasmic reticulum calcium ATPase in β-cells
PD Borge et al.
DIABETES (2002)
Involvement of the ryanodine-sensitive Ca2+ store in GLP-1-induced Ca2+ oscillations in insulin-secreting HIT cells
S Sasaki et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2002)
cAMP-activated protein kinase-independent potentiation of insulin secretion by cAMP is impaired in SUR1 null islets
M Nakazaki et al.
DIABETES (2002)
Protein kinase C-ε (PKC-ε):: Its unique structure and function
Y Akita
JOURNAL OF BIOCHEMISTRY (2002)
Differential roles of Ras and Rap1 in growth factor-dependent activation of phospholipase Cε
CH Song et al.
ONCOGENE (2002)
Sulfonylurea receptor type 1 knock-out mice have intact feeding-stimulated insulin secretion despite marked impairment in their response to glucose
C Shiota et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Glucose-induced β cell production of IL-1β contributes to glucotoxicity in human pancreatic islets
K Maedler et al.
JOURNAL OF CLINICAL INVESTIGATION (2002)
Glucagon-like peptide-1 inhibits pancreatic ATP-sensitive potassium channels via a protein kinase A- and ADP-dependent mechanism
PE Light et al.
MOLECULAR ENDOCRINOLOGY (2002)
β-cell function is a major contributor to oral glucose tolerance in high-risk relatives of four ethnic groups in the US
CC Jensen et al.
DIABETES (2002)
Human neuropathy target esterase catalyzes hydrolysis of membrane lipids
M van Tienhoven et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Inhibition of interleukin-1β-induced COX-2 and EP3 gene expression by sodium salicylate enhances pancreatic islet β-cell function
POT Tran et al.
DIABETES (2002)
Stimulation of insulin secretion and associated nuclear accumulation of iPLA2β in INS-1 insulinoma cells
ZM Ma et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2002)
The biochemistry of n-3 polyunsaturated fatty acids
DB Jump
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Is reduced first-phase : Insulin release the earliest detectable abnormality in individuals destined to develop type 2 diabetes?
JE Gerich
DIABETES (2002)
Critical role of cAMP-GEFII.Rim2 complex in incretin-potentiated insulin secretion
Y Kashima et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Studies of phospholipid metabolism, proliferation, and secretion of stably transfected insulinoma cells that overexpress group VIA phospholipase A2
ZM Ma et al.
LIPIDS (2001)
CREB-binding protein and p300 in transcriptional regulation
N Vo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Distinct effects of saturated and monounsaturated fatty acids on beta-cell turnover and function
K Maedler et al.
DIABETES (2001)
cAMP-GEFII is a direct target of cAMP in regulated exocytosis
N Ozaki et al.
NATURE CELL BIOLOGY (2000)
Triggering and amplifying pathways of regulation of insulin secretion by glucose
JC Henquin
DIABETES (2000)
Distinct roles of two intracellular phospholipase A2s in fatty acid release in the cell death pathway -: Proteolytic fragment of type IVA cytosolic phospholipase A2α inhibits stimulus-induced arachidonate release, whereas that of type VICa2+-independent phospholipase A2 augments spontaneous fatty acid release
G Atsumi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Islet phospholipase A2 activation is potentiated in insulin resistant mice
E Simonsson et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
Sphingosine 1-phosphate stimulates insulin secretion in HIT-T 15 cells and mouse islets
H Shimizu et al.
ENDOCRINE JOURNAL (2000)
The Rab3-interacting molecule RIM is expressed in pancreatic β-cells and is implicated in insulin exocytosis
M Iezzi et al.
FEBS LETTERS (2000)
The genomic organization, complete mRNA sequence, cloning, and expression of a novel human intracellular membrane-associated calcium-independent phospholipase A2
DJ Mancuso et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Adenylyl cyclase isoform expression in non-diabetic and diabetic Goto-Kakizaki (GK) rat pancreas. Evidence for distinct overexpression of type-8 adenylyl cyclase in diabetic GK rat islets
A Guenifi et al.
HISTOCHEMISTRY AND CELL BIOLOGY (2000)