Solvent-directed multiple correspondence fluorescent probe for highly selective and sensitive detection of Cu2+and Mg2+

A solvent-directed, new Schiff base multiple correspondence fluorescent probe, (E)-2-(2-hydroxybenzylidene) hydrazine-1-carboxamid (L), was synthesized for selective sensing of Cu2+ and Mg2+ ions. L showed excellent selectivity and high sensitivity toward Cu2+ in turn off mode with a detection limit of 40.5 nM in 10 mM, pH = 7.0 PBS buffer. Contrary to that, when acetonitrile was used as the solvent, L exhibited highly selective and sensitive fluorescence sensing ability for Mg2+ in turn on mode with a detection limit of 9.5 nM. L can coordinate to Cu2+ and Mg2+ in a 1:1 molar ratio, respectively, evidenced by Job's plot analysis. Their binding modes were investigated by NMR, IR and XPS spectroscopies. Moreover, the satisfied results were obtained when L was used to detect Cu2+ and Mg2+ in real water samples.

Automated summary

A new Schiff base multiple correspondence fluorescent probe, (E)-2-(2-hydroxybenzylidene) hydrazine-1-carboxamid (L), was synthesized for selective sensing of Cu2+ and Mg2+ ions. L showed excellent selectivity and high sensitivity toward Cu2+ in turn off mode with a detection limit of 40.5 nM in 10 mM, pH = 7.0 PBS buffer. On the other hand, L exhibited highly selective and sensitive fluorescence sensing ability for Mg2+ in turn on mode with a detection limit of 9.5 nM when acetonitrile was used as the solvent. The binding modes of L with Cu2+ and Mg2+ were investigated, and satisfactory results were obtained when L was used to detect Cu2+ and Mg2+ in real water samples.