STRIKE-GOLDD 4.0: user-friendly, efficient analysis of structural identifiability and observability

Motivation: STRIKE-GOLDD is a toolbox that analyses the structural identifiability and observability of possibly non-linear, non-rational ODE models that may have known and unknown inputs. Its broad applicability comes at the expense of a lower computational efficiency than other tools. Results: STRIKE-GOLDD 4.0 includes a new algorithm, ProbObsTest, specifically designed for the analysis of rational models. ProbObsTest is significantly faster than the previously available FISPO algorithm when applied to computationally expensive models. Providing both algorithms in the same toolbox allows combining generality and computational efficiency. STRIKE-GOLDD 4.0 is implemented as a Matlab toolbox with a user-friendly graphical interface.

Automated summary

STRIKE-GOLDD is a toolbox that analyzes the structural identifiability and observability of possibly non-linear, non-rational ODE models with known and unknown inputs. Its broad applicability may result in lower computational efficiency than other tools. The new algorithm, ProbObsTest, significantly improves computational speed when applied to computationally expensive models, making it a valuable addition to STRIKE-GOLDD 4.0.