Journal
RSC ADVANCES
Volume 6, Issue 13, Pages 10873-10879Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ra24851e
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Funding
- All India Council of Technical Education (AICTE), New Delhi [8023/BOR/RID/RPS (NER)-68/2010-11]
- MHRD, Govt. of India
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A novel, efficient, and high-yielding method was developed for the synthesis of 3-sulfenylindoles via a DBU-based ionic liquid promoted sulfenylation of indoles using sulfonyl hydrazides as a thiol surrogate. The environmentally friendly procedure, easy operation and mild reaction conditions enable the tolerance of a wide scope of functionalities as well as high reaction efficiency. The synthetic procedure is suitable for both N-protected or unprotected indoles.
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