Journal
RSC ADVANCES
Volume 6, Issue 67, Pages 62406-62410Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6ra12127f
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Funding
- NSFC [21172063, 21472067, 21502067]
- Natural Science Foundation of Shandong Province, China [ZR2014BP001]
- Taishan Scholar Foundation [TS 201511041]
- University of Jinan [160082101]
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Through an intramolecular nucleophilic substitution reaction and ESIPT mechanism, we designed and synthesized a fluorescent hydrogen sulfide probe with a large turn on fluorescence signal (400-fold). The new probe exhibits high selectivity, good membrane-permeability and is suitable for the visualization of exogenous and endogenous hydrogen sulfide in living cells.
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