Related references
Note: Only part of the references are listed.
Review
Microbiology
Hannah E. Davis et al.
Summary: Long COVID is a common and debilitating illness that affects at least 10% of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, with a wide range of symptoms and impacts on multiple organ systems. There are an estimated 65 million individuals worldwide with long COVID, and the number of cases is increasing daily. Current diagnostic and treatment options are insufficient, and there is a need for clinical trials to address leading hypotheses. Future research should account for biases and testing issues, build on viral-onset research, include marginalized populations, and meaningfully engage patients.
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(2023)
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Critical Care Medicine
Chloe Saunders et al.
Lancet Respiratory Medicine
(2023)
Review
Medicine, General & Internal
Lauren L. O'Mahoney et al.
Summary: This study systematically synthesized global evidence on the prevalence of persistent symptoms in a general post COVID-19 population. The findings show that regardless of hospitalization status, at least 45% of COVID-19 survivors experience unresolved symptoms for about 4 months. The current understanding of Long Covid is limited by heterogeneous study design, follow-up durations, and measurement methods, hindering effective treatment and management strategies.
Article
Medicine, General & Internal
Silvana Luciani et al.
Summary: This article summarizes the results of the WHO non-communicable diseases (NCDs) Country Capacity Survey in the Americas region from 2019 to 2021, focusing on NCD service capacity and disruptions caused by the COVID-19 pandemic. Information on primary care services for NCDs and related technical inputs from 35 countries in the region are provided. The findings reveal significant disruptions in NCD services due to the pandemic, with a lack of comprehensive NCD guidelines, essential medicines, and related service inputs reported by more than 50% of countries.
Editorial Material
Rheumatology
Aurelie Najm et al.
Review
Rheumatology
Hem Raj Sapkota et al.
Summary: Long COVID, a long-term sequel of acute COVID-19, presents persistent or relapsing symptoms such as fatigue, breathlessness, and myalgia, which can be difficult to differentiate from rheumatic diseases.
CLINICAL RHEUMATOLOGY
(2022)
Review
Medicine, General & Internal
D. Castanares-Zapatero et al.
Summary: After almost 2 years of fighting against the SARS-CoV-2 pandemic, the number of patients experiencing persistent symptoms long after acute infection is concerning. This condition, known as long COVID or Post COVID-19 condition, has an unclear underlying pathophysiology. A comprehensive review was conducted to explore potential mechanisms for the persisting symptoms, such as organ damage, autonomic nervous system damage, immune dysregulation, auto-immunity, endothelial dysfunction, occult viral persistence, and coagulation activation.
ANNALS OF MEDICINE
(2022)
Review
Immunology
Felicia Ceban et al.
Summary: Post-COVID-19 syndrome, characterized by persistent symptoms after resolution of acute infection, is associated with significant fatigue and cognitive impairment. This study aimed to quantify the proportion of individuals experiencing fatigue and cognitive impairment 12 or more weeks after COVID-19 diagnosis, and to explore the inflammatory and functional consequences of post-COVID-19 syndrome. The results showed that a significant proportion of individuals continue to experience fatigue and cognitive impairment even after 12 or more weeks of COVID-19 diagnosis. Additionally, some individuals showed elevated levels of inflammatory markers and significant functional impairment.
BRAIN BEHAVIOR AND IMMUNITY
(2022)
Review
Biochemistry & Molecular Biology
Rehan M. El-Shabasy et al.
Summary: It has been over a year since the first case of COVID-19 was reported in China. The world has witnessed three waves of the virus, with varying characteristics and challenges. Despite a decrease in the sense of danger in most countries, the emergence of new variant strains has raised concerns again. The mutations in COVID-19 have presented an extreme challenge in preventing and treating the virus, and there are still many unanswered questions about the effectiveness of vaccines and the need for annual doses.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Review
Immunology
Chen Chen et al.
Summary: This study reveals a substantial prevalence of post-COVID-19 condition worldwide. Hospitalized patients have a higher prevalence compared to non-hospitalized ones. Fatigue is the most commonly reported symptom.
JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Environmental Sciences
Florent Besnier et al.
Summary: The COVID-Rehab study investigates the effectiveness of an eight-week cardiopulmonary rehabilitation program for long-term COVID-19 patients. The study examines multiple outcomes including cardiorespiratory fitness, quality of life, and cognition. The findings will provide important guidance for the rehabilitation of long-term COVID-19 patients.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Review
Environmental Sciences
Stefania Fugazzaro et al.
Summary: This systematic review investigates the effectiveness of rehabilitation interventions for individuals with post-acute COVID-19 syndrome (PACS). The study suggests that rehabilitation can improve dyspnea, anxiety, and kinesiophobia, although results on pulmonary function are inconsistent. However, improvements were detected in muscle strength, walking capacity, sit-to-stand performance, and quality of life. Further high-quality studies are needed to confirm these findings.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Rheumatology
Anna Molto et al.
Summary: The study aimed to determine the prevalence of musculoskeletal symptoms following a SARS-CoV2 infection, and found that nearly 9% of patients admitted to the hospital after a SARS-CoV-2 infection developed musculoskeletal symptoms, with back pain and joint pain being the most common. Older age, obesity, hypertension, and diabetes were identified as risk factors for the development of musculoskeletal symptoms.
Editorial Material
Medicine, General & Internal
Christina Pagel
BMJ-BRITISH MEDICAL JOURNAL
(2022)
Review
Chemistry, Multidisciplinary
Alessandro de Sire et al.
Summary: This systematic review aimed to evaluate the efficacy of rehabilitation treatment on fatigue in post-COVID-19 patients. The findings showed that rehabilitation treatment can effectively reduce fatigue in patients, with only a small percentage experiencing persistent symptoms after treatment.
APPLIED SCIENCES-BASEL
(2022)
Review
Chemistry, Multidisciplinary
Lucrezia Tognolo et al.
Summary: Spa therapy has shown favorable effects on pain, function, and quality of life in patients with Osteoarthritis, Fibromyalgia, and Rheumatoid Arthritis. The combination of thermal therapy and rehabilitation treatments has shown better clinical outcomes.
APPLIED SCIENCES-BASEL
(2022)
Article
Rehabilitation
Jamie Wilcox et al.
Summary: This case report describes occupational therapy evaluation and treatment approaches, plan of care, and associated outcomes for one client experiencing long COVID symptoms in the outpatient setting, using evidence-based practice strategies.
AMERICAN JOURNAL OF OCCUPATIONAL THERAPY
(2021)
Article
Rehabilitation
Maria Chiara Maccarone et al.
Summary: Since the outbreak of the COVID-19 pandemic in March 2020, the healthcare systems worldwide have been focusing on fighting the pandemic, but the rehabilitation needs of patients with other diseases cannot be ignored. Our rehabilitation unit managed to maintain communication with patients through alternative methods and took preventive measures to ensure the safety of face-to-face treatments.
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
(2021)
News Item
Critical Care Medicine
Priya Venkatesan
LANCET RESPIRATORY MEDICINE
(2021)
Review
Nursing
Chiyoung Cha et al.
Summary: The scoping review aimed to describe symptoms and management of long COVID conditions, with limited evidence-based guidelines for multidisciplinary management found in the literature. Long COVID symptoms included dyspnoea, anosmia/ageusia, fatigue, and cough, with management approaches focusing on multidisciplinary care, pulmonary rehabilitation, fatigue management, and psychological therapy.
JOURNAL OF CLINICAL NURSING
(2021)
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Neurosciences
Daniele Coraci et al.
Summary: This study conducted a lexical analysis of literature on ultrasound use in peripheral neuropathies, highlighting the importance of ultrasound in therapy and identifying the United States as the most productive country in this field. The results provide valuable insights for understanding and evaluating the current literature on this topic.
Article
Respiratory System
Dominic L. Sykes et al.
Summary: Recent studies have shown that COVID-19 patients may experience lasting symptoms, with females being more likely to report residual symptoms. The phenomenon of Long-COVID may not be solely attributed to the impact of SARS-CoV-2, indicating a potential role of biopsychosocial effects of COVID-19 in its etiology.
Article
Environmental Sciences
Andres Ayala et al.
Summary: Identifying COVID-19 waves is crucial for research and decision making. This study presents a quantitative method based on weekly accumulated incidence rates to define waves, showing that longer study periods lead to worse model fit. The research underscores the importance of well-defined definitions for COVID-19 waves and their impact on both research and policy making.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
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Stefano Masiero et al.
INTERNATIONAL JOURNAL OF BIOMETEOROLOGY
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Review
Medicine, General & Internal
Hikmet Akkiz
Summary: This article discusses the effects of novel mutations in the SARS-CoV-2 genome on transmission, clinical outcomes, and vaccine development. It highlights the impact of the D614G mutation and three new variants on virus characteristics and vaccine efficacy.
FRONTIERS IN MEDICINE
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Environmental Sciences
Maria Chiara Maccarone et al.
Summary: Recent evidence suggests that inhalations and mineral-rich water immersions in a spa setting are effective in fighting and preventing multiple chronic respiratory tract diseases. Therefore, these treatments could also be beneficial for post-COVID patients with medium long-term respiratory outcomes.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
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Article
Environmental Sciences
Maria Chiara Maccarone et al.
Summary: The public interest in balneotherapy has changed in the COVID-19 era in both Italy and Japan. During the early stage of the pandemic (March to June), interest was lower, but later recovered in both countries. In Italy, population interest reached prior levels from late June to early October, peaking in August. In Japan, interest exceeded prior levels from mid-September to early November before declining in both countries, starting in early October for Italy and late November for Japan.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Review
Infectious Diseases
Hossein Akbarialiabad et al.
Summary: This study provides a review of literature on Long COVID until January 30, 2021, revealing controversies in its definition and predominant symptoms such as fatigue, breathlessness, and arthralgia. Potential long-term sequelae include cutaneous, respiratory, cardiovascular involvement, among others.
Letter
Biophysics
Maria Chiara Maccarone et al.
Summary: The use of spa resources may help in treating chronic fatigue caused by COVID-19 sequelae, providing multidisciplinary interventions and rehabilitation protocols to assist patients in regaining their health.
INTERNATIONAL JOURNAL OF BIOMETEOROLOGY
(2021)
Review
Medicine, General & Internal
Olalekan Lee Aiyegbusi et al.
Summary: Patients with long COVID experience a wide range of physical and mental symptoms, with common issues including fatigue, shortness of breath, and headaches. Beyond symptoms and complications, they often report impaired quality of life, mental health issues, and employment problems.
JOURNAL OF THE ROYAL SOCIETY OF MEDICINE
(2021)
Review
Virology
Ivana Lazarevic et al.
Summary: Although SARS-CoV-2 evolves slowly compared to other RNA viruses, its rapid transmission during the COVID-19 pandemic has led to the emergence of numerous variants, some of which have been labeled as variants of concern. These variants may have an impact on transmission, morbidity/mortality, and evasion of neutralization by antibodies, especially monoclonal antibodies.
Article
Multidisciplinary Sciences
Sandra Lopez-Leon et al.
Summary: This study aimed to identify studies assessing the long-term effects of COVID-19, estimating that 80% of infected patients will develop one or more long-term symptoms, with the most common being fatigue, headache, attention disorder, hair loss, and dyspnea.
SCIENTIFIC REPORTS
(2021)
Review
Immunology
Carolina X. Sandler et al.
Summary: Fatigue is a prominent feature in both acute and convalescent stages of COVID-19, with lasting effects on long-term recovery. Studying post-COVID fatigue and fatigue after other infections can provide valuable insights into clinical and research approaches to assess and address this issue.
OPEN FORUM INFECTIOUS DISEASES
(2021)
Article
Critical Care Medicine
Davide Chiumello et al.
Summary: This study found that the effects of raising PEEP in COVID-19 ARDS patients during the early phase are highly variable and cannot be easily predicted based on respiratory system characteristics due to the heterogeneity of the disease.
Review
Public, Environmental & Occupational Health
Melina Michelen et al.
Summary: Long COVID is a complex condition with prolonged and heterogeneous symptoms, including weakness, general malaise, fatigue, concentration impairment, and breathlessness. Approximately 37% of patients reported reduced quality of life, and 26% of studies presented evidence of reduced pulmonary function. There is an urgent need for further studies to explore the etiology, risk factors, and biomarkers of long COVID in different populations and settings.
Article
Endocrinology & Metabolism
A. V. Raveendran et al.
Summary: Long COVID refers to the persistence of symptoms in individuals who have recovered from SARS-CoV-2 infection, possibly related to organ damage, post viral syndrome, etc. Clinical evaluation should focus on identifying the pathophysiology and appropriate remedial measures.
DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS
(2021)
Review
Rehabilitation
Francesco Agostini et al.
Summary: An integrated rehabilitative approach is recommended for COVID-19 patients, involving a multidisciplinary team providing neuromuscular, cardiac, respiratory, and swallowing interventions, as well as psychological support, to improve patients' quality of life. The involvement of a physician expert in rehabilitation is key, with a dedicated intervention set up after thorough assessment of the patient's clinical condition in collaboration with all rehabilitation team professionals.
JOURNAL OF REHABILITATION MEDICINE
(2021)
Article
Sport Sciences
Robert M. Barker-Davies et al.
BRITISH JOURNAL OF SPORTS MEDICINE
(2020)
Letter
Virology
Daniele Coraci et al.
JOURNAL OF MEDICAL VIROLOGY
(2020)
Letter
Anesthesiology
Daniele Coraci et al.
Letter
Biophysics
Stefano Masiero et al.
INTERNATIONAL JOURNAL OF BIOMETEOROLOGY
(2020)
Article
Neurosciences
M. Reza Azarpazhooh et al.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2020)
Article
Medicine, General & Internal
Alarcos Cieza et al.
Review
Health Care Sciences & Services
Mark Vink et al.
Article
Respiratory System
Michele Vitacca et al.
MONALDI ARCHIVES FOR CHEST DISEASE
(2020)
