Journal
RSC ADVANCES
Volume 6, Issue 26, Pages 21535-21539Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ra26931h
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Funding
- National Natural Science Foundation of China [21372137, 21572110]
- Natural Science Foundation of Shandong Province [ZR2014BM006]
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beta-Ketothioamides (KTAs) have been used as building blocks with aldehydes and beta-enaminonitriles for synthesis of 1,4-dihydropyridines in the presence of AcOH under solvent-free conditions within 5 min. This new strategy exhibits remarkable features such as high chemoselectivity, mild reaction conditions, easily available substrates, and good yields.
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