Journal
RSC ADVANCES
Volume 6, Issue 79, Pages 75202-75206Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6ra13371a
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Funding
- Research Fund - Flanders (FWO)
- Research Fund of the University of Leuven (KU Leuven)
- University of Leuven (KU Leuven)
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A diversity-oriented approach for the synthesis of 2-aminoimidazoles is presented. The method involves the cyclization of secondary propargylamines using iodine allowing the generation of diversely-substituted 2-aminoimidazoles. The iodo group generated during cyclization can be used for further modification, which is an additional asset of this method.
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